ID   DCTN6_XENTR             Reviewed;         201 AA.
AC   Q28DR7;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   04-APR-2006, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Dynactin subunit 6;
GN   Name=dctn6; ORFNames=TGas061c09.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Gastrula;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Member of the pointed-end complex of the dynactin shoulder
CC       complex which contains dctn4, dctn5 and dctn6 subunits and Actr10.
CC       Within the complex dctn6 forms a heterodimer with dctn5. Interacts with
CC       plk1 (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}.
CC       Chromosome, centromere, kinetochore {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the dynactin subunits 5/6 family. Dynactin
CC       subunit 6 subfamily. {ECO:0000305}.
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DR   EMBL; CR848630; CAJ83606.1; -; mRNA.
DR   EMBL; BC135759; AAI35760.1; -; mRNA.
DR   RefSeq; NP_001039059.1; NM_001045594.1.
DR   AlphaFoldDB; Q28DR7; -.
DR   SMR; Q28DR7; -.
DR   STRING; 8364.ENSXETP00000022598; -.
DR   PaxDb; Q28DR7; -.
DR   DNASU; 733845; -.
DR   GeneID; 733845; -.
DR   KEGG; xtr:733845; -.
DR   CTD; 10671; -.
DR   eggNOG; KOG4042; Eukaryota.
DR   HOGENOM; CLU_085418_1_0_1; -.
DR   InParanoid; Q28DR7; -.
DR   OMA; PDYTVVY; -.
DR   OrthoDB; 1278795at2759; -.
DR   PhylomeDB; Q28DR7; -.
DR   TreeFam; TF352888; -.
DR   Proteomes; UP000008143; Chromosome 1.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005869; C:dynactin complex; IEA:InterPro.
DR   GO; GO:0000776; C:kinetochore; IEA:UniProtKB-KW.
DR   InterPro; IPR027777; DCTN6.
DR   InterPro; IPR001451; Hexapep.
DR   InterPro; IPR011004; Trimer_LpxA-like_sf.
DR   PANTHER; PTHR13072; PTHR13072; 1.
DR   Pfam; PF00132; Hexapep; 1.
DR   SUPFAM; SSF51161; SSF51161; 1.
PE   2: Evidence at transcript level;
KW   Centromere; Chromosome; Cytoplasm; Cytoskeleton; Kinetochore;
KW   Reference proteome.
FT   CHAIN           1..201
FT                   /note="Dynactin subunit 6"
FT                   /id="PRO_0000327737"
SQ   SEQUENCE   201 AA;  21918 MW;  F1AD43487460B045 CRC64;
     MRQDVSLLST SGSQKNPLGN VKIAPGAVVC VESEIKGDVT IGPRTVVHPK ARIYAEAGPI
     IIGEGNLIEE QAFIRNSFPE NIAPDSDVEP KTMIIGTNNV FEVGCYSQAM KMGDNNVIES
     KAFVGRNVIL TSGCIIGACC QVDTCEVIPE NTVIYGSDCL RRVQTERPQP QTLQLDFLMK
     ILPNYHHLKK TTKNISTPMK S