ID   DCTQ_VIBCH              Reviewed;         232 AA.
AC   Q9KQS0;
DT   20-JAN-2016, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 71.
DE   RecName: Full=C4-dicarboxylate TRAP transporter small permease protein DctQ {ECO:0000305};
GN   Name=dctQ {ECO:0000303|PubMed:22556361};
GN   OrderedLocusNames=VC_1928 {ECO:0000312|EMBL:AAF95076.1};
OS   Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=243277;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39315 / El Tor Inaba N16961;
RX   PubMed=10952301; DOI=10.1038/35020000;
RA   Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA   Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA   Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D.,
RA   Vamathevan J.J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.A.,
RA   Utterback T.R., Fleischmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA   Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT   "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT   cholerae.";
RL   Nature 406:477-483(2000).
RN   [2]
RP   PROBABLE FUNCTION.
RX   PubMed=22556361; DOI=10.1099/mic.0.059659-0;
RA   Chowdhury N., Norris J., McAlister E., Lau S.Y., Thomas G.H., Boyd E.F.;
RT   "The VC1777-VC1779 proteins are members of a sialic acid-specific subfamily
RT   of TRAP transporters (SiaPQM) and constitute the sole route of sialic acid
RT   uptake in the human pathogen Vibrio cholerae.";
RL   Microbiology 158:2158-2167(2012).
CC   -!- FUNCTION: Part of the tripartite ATP-independent periplasmic (TRAP)
CC       transport system DctPQM involved in C4-dicarboxylates uptake.
CC       {ECO:0000305|PubMed:22556361}.
CC   -!- SUBUNIT: The complex comprises the extracytoplasmic solute receptor
CC       protein DctP, and the two transmembrane proteins DctQ and DctM.
CC       {ECO:0000250|UniProtKB:O07837}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000250|UniProtKB:O07837}; Multi-pass membrane protein
CC       {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the TRAP transporter small permease family.
CC       {ECO:0000305}.
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DR   EMBL; AE003852; AAF95076.1; -; Genomic_DNA.
DR   PIR; E82140; E82140.
DR   RefSeq; NP_231562.1; NC_002505.1.
DR   AlphaFoldDB; Q9KQS0; -.
DR   STRING; 243277.VC_1928; -.
DR   DNASU; 2613557; -.
DR   EnsemblBacteria; AAF95076; AAF95076; VC_1928.
DR   KEGG; vch:VC_1928; -.
DR   PATRIC; fig|243277.26.peg.1845; -.
DR   eggNOG; COG3090; Bacteria.
DR   HOGENOM; CLU_086356_3_2_6; -.
DR   OMA; LEWPTWI; -.
DR   BioCyc; VCHO:VC1928-MON; -.
DR   Proteomes; UP000000584; Chromosome 1.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0015740; P:C4-dicarboxylate transport; IBA:GO_Central.
DR   InterPro; IPR007387; TRAP_DctQ.
DR   PANTHER; PTHR35011; PTHR35011; 1.
DR   Pfam; PF04290; DctQ; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..232
FT                   /note="C4-dicarboxylate TRAP transporter small permease
FT                   protein DctQ"
FT                   /id="PRO_0000435383"
FT   TRANSMEM        30..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        58..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        103..123
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        167..187
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   232 AA;  26773 MW;  51F0084C045F7D9C CRC64;
     MSVRHTIRAM YHMEQSWFSR VGQFTDSIEE FLIAFFMGAM TLLTFANVIM RYLFNDNILW
     ALEGTVFMFA WMVLVGASFG VKRHFHIGVD VLINIAPARL RKLYALVAVA CCLAFSILLL
     IGSWNYWHPF ITERAWYETD DIPMPDMLQF LADWVNEGER YEKLPRFIPY AALPIGMALL
     TFRFLQIAWQ IITGKLDRMI AGHEAEEDLE ALKAELSEAG EAMMPKTQGK EK