ID   DCTR_ALKHC              Reviewed;         230 AA.
AC   Q9K998;
DT   14-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 134.
DE   RecName: Full=Probable C4-dicarboxylate response regulator DctR;
GN   Name=dctR; OrderedLocusNames=BH2751;
OS   Alkalihalobacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344
OS   / JCM 9153 / C-125) (Bacillus halodurans).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Alkalihalobacillus.
OX   NCBI_TaxID=272558;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125;
RX   PubMed=11058132; DOI=10.1093/nar/28.21.4317;
RA   Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F.,
RA   Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K.;
RT   "Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans
RT   and genomic sequence comparison with Bacillus subtilis.";
RL   Nucleic Acids Res. 28:4317-4331(2000).
CC   -!- FUNCTION: Member of the two-component regulatory system DctS/DctR.
CC       Essential for expression of DctP (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- PTM: Phosphorylated by DctS. {ECO:0000250}.
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DR   EMBL; BA000004; BAB06470.1; -; Genomic_DNA.
DR   PIR; G83993; G83993.
DR   RefSeq; WP_010898899.1; NC_002570.2.
DR   AlphaFoldDB; Q9K998; -.
DR   SMR; Q9K998; -.
DR   STRING; 272558.10175372; -.
DR   EnsemblBacteria; BAB06470; BAB06470; BAB06470.
DR   KEGG; bha:BH2751; -.
DR   eggNOG; COG4565; Bacteria.
DR   HOGENOM; CLU_000445_39_0_9; -.
DR   OMA; MRHGALQ; -.
DR   OrthoDB; 1755994at2; -.
DR   Proteomes; UP000001258; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR024187; Sig_transdc_resp-reg_cit/mal.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR45526; PTHR45526; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   PIRSF; PIRSF006171; RR_citrat_malat; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF52172; SSF52172; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   3: Inferred from homology;
KW   Activator; Cytoplasm; DNA-binding; Phosphoprotein; Reference proteome;
KW   Transcription; Transcription regulation; Two-component regulatory system.
FT   CHAIN           1..230
FT                   /note="Probable C4-dicarboxylate response regulator DctR"
FT                   /id="PRO_0000081090"
FT   DOMAIN          8..124
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT   DNA_BIND        183..209
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255"
FT   MOD_RES         59
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   230 AA;  26376 MW;  06FD65F46FC57D40 CRC64;
     MAKEPLIRVL LIEDDPMVQE VNRMFVEKLS GFTIVGTTAT GEEGMVKTRE LQPDLILLDI
     FMPKQDGLSF IKQIREQYID VDIIAVTAAN DTKTIKTLLR YGVMDYLVKP FTFERLKAAL
     TQYEEMFRKM QKEAELSQDS LDEMIKQKQA QANMDDLPKG LHAHTLQQVI ERLEELDEPK
     SAEEIGRDVG LARVTVRRYL NYLESVGQVE MDLTYGSIGR PIQTYKLKQG