ID   ACT_HYPJE               Reviewed;         376 AA.
AC   Q99023;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Actin;
GN   Name=act;
OS   Hypocrea jecorina (Trichoderma reesei).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX   NCBI_TaxID=51453;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 56765 / Rut C-30;
RX   PubMed=7642121; DOI=10.1016/0378-1119(95)00283-c;
RA   Matheucci E. Jr., Henrique-Silva F., El-Gogary S., Rossini C.H., Leite A.,
RA   Vera J.E., Urioste J.C.C., Crivellaro O., El-Dorry H.;
RT   "Structure, organization and promoter expression of the actin-encoding gene
RT   in Trichoderma reesei.";
RL   Gene 161:103-106(1995).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR   EMBL; X75421; CAA53173.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q99023; -.
DR   SMR; Q99023; -.
DR   PRIDE; Q99023; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding.
FT   CHAIN           1..376
FT                   /note="Actin"
FT                   /id="PRO_0000089045"
SQ   SEQUENCE   376 AA;  41745 MW;  5916B0DB6C87196B CRC64;
     MEEEVAALVI DNGSGMCKAG FAGDDAPRAV FPSIDGRSRH HGIMIGMGQK DSYVGDEAQS
     KRGILTLRYP IEHGVVTNWD DMEKIWHHTF YNELRVAPEE HPVLLTEAPI NPKSNREKMT
     QIMFETFNAP AFYVSIQAVL SLYASGRTTG IVLDSGDGVT TVVPIYEGFA LPHAIRRVDM
     AGRDLTDYLM KILAERGYTF STTAEREIVR DIKEKLCYVA HDFEQEIQTA AQSSSLEKSY
     ELPDAQVITI GDRFRAPQAL FHASVLGLES AGIDVTTFNS IMKCDVDVRK ELYGNIVMSG
     GTTMFPQGIS DRMQKEITAS APSSAMKVKI IAPPERKYSV WIGGSILASL TTFQQMWISK
     QEYDESGPSI VHHKCF