ID   DCTR_PRIMG              Reviewed;         228 AA.
AC   P39486;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   25-MAY-2022, entry version 115.
DE   RecName: Full=Probable C4-dicarboxylate response regulator DctR;
GN   Name=dctR;
OS   Priestia megaterium (Bacillus megaterium).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Priestia.
OX   NCBI_TaxID=1404;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=IAM 1030 / JCM 20016;
RA   Mitamura T., Ebora R.V., Nakai T., Makino Y., Negoro S., Urabe I.,
RA   Okada H.;
RT   "Structure of isozyme genes of glucose dehydrogenase from Bacillus
RT   megaterium IAM1030.";
RL   J. Ferment. Bioeng. 70:363-369(1990).
CC   -!- FUNCTION: Member of the two-component regulatory system DctS/DctR.
CC       Essential for expression of DctP (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- PTM: Phosphorylated by DctS. {ECO:0000250}.
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DR   EMBL; D90043; BAA14097.1; -; Genomic_DNA.
DR   PIR; I39850; JS0383.
DR   RefSeq; WP_013081863.1; NZ_UFSS01000001.1.
DR   AlphaFoldDB; P39486; -.
DR   SMR; P39486; -.
DR   PATRIC; fig|1404.33.peg.5370; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR006793; FaeA.
DR   InterPro; IPR024187; Sig_transdc_resp-reg_cit/mal.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR45526; PTHR45526; 1.
DR   Pfam; PF04703; FaeA; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   PIRSF; PIRSF006171; RR_citrat_malat; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF52172; SSF52172; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   3: Inferred from homology;
KW   Activator; Cytoplasm; DNA-binding; Phosphoprotein; Transcription;
KW   Transcription regulation; Two-component regulatory system.
FT   CHAIN           1..228
FT                   /note="Probable C4-dicarboxylate response regulator DctR"
FT                   /id="PRO_0000081091"
FT   DOMAIN          7..123
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT   DNA_BIND        180..199
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255"
FT   MOD_RES         58
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   228 AA;  26214 MW;  60482CFAFA0BD4A4 CRC64;
     MNKKAWTVLL IEDDPMVQEV NRQFIEQVEG FTVIAAASNG LEGVQLIKQH QPDLTIIDMY
     MPSQDGLTTL QQIRANGYKT DVIAVTAASD IETVRKVLQY GAVDYIMKPF KFERMKQALE
     QYRSFQVKIS QKEHITQSEL DSMLFQQFEE KADLLPKGLN AVTLRRIQQY LSEQNHPISA
     EEVADGVGIA RVTARRYLEF LEQENELKLS VEYGRVGRPI NRYMLKIN