ID   DCTR_RHOCA              Reviewed;         197 AA.
AC   P37740;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   25-MAY-2022, entry version 108.
DE   RecName: Full=C4-dicarboxylate transport transcriptional regulatory protein DctR;
GN   Name=dctR;
OS   Rhodobacter capsulatus (Rhodopseudomonas capsulata).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Rhodobacter.
OX   NCBI_TaxID=1061;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 33303 / B10;
RX   PubMed=8455557; DOI=10.1007/bf00282803;
RA   Hamblin M.J., Shaw J.G., Kelly D.J.;
RT   "Sequence analysis and interposon mutagenesis of a sensor-kinase (DctS) and
RT   response-regulator (DctR) controlling synthesis of the high-affinity C4-
RT   dicarboxylate transport system in Rhodobacter capsulatus.";
RL   Mol. Gen. Genet. 237:215-224(1993).
CC   -!- FUNCTION: Member of the two-component regulatory system DctS/DctR
CC       involved in the transport of C4-dicarboxylates. DctR functions as a
CC       transcriptional repressor of genes for C4-dicarboxylate transport.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- PTM: Phosphorylated by DctS.
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DR   EMBL; X64733; CAA46000.1; -; Genomic_DNA.
DR   PIR; S30289; S30289.
DR   RefSeq; WP_013068723.1; NZ_VIBE01000005.1.
DR   AlphaFoldDB; P37740; -.
DR   SMR; P37740; -.
DR   GeneID; 31491818; -.
DR   OMA; DACEGGR; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd06170; LuxR_C_like; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF00196; GerE; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   PRINTS; PR00038; HTHLUXR.
DR   SMART; SM00421; HTH_LUXR; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF52172; SSF52172; 1.
DR   PROSITE; PS00622; HTH_LUXR_1; 1.
DR   PROSITE; PS50043; HTH_LUXR_2; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   3: Inferred from homology;
KW   Activator; Cytoplasm; DNA-binding; Phosphoprotein; Transcription;
KW   Transcription regulation; Two-component regulatory system.
FT   CHAIN           1..197
FT                   /note="C4-dicarboxylate transport transcriptional
FT                   regulatory protein DctR"
FT                   /id="PRO_0000081093"
FT   DOMAIN          4..120
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT   DOMAIN          136..197
FT                   /note="HTH luxR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00411"
FT   DNA_BIND        160..179
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00411"
FT   REGION          128..135
FT                   /note="Inter-domain linker"
FT                   /evidence="ECO:0000255"
FT   MOD_RES         53
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   197 AA;  21271 MW;  C5F72003FCAC0AD4 CRC64;
     MSFTVHIVDD EESLRDSLGF LFASRGIATR TWAAGADLLA EWPLADCGCL ILDVRMEGMS
     GPQLLDALQA RPEGLVPPVI FLTGHADVPL AVQSLKAGAF DFVEKPFNDN HIVDIALSAI
     AAHEGRLAEA QAREAVAARR ASLSAREAEV MALMLEGLMN KQIAERLGIA MRTVEVHRSR
     VLAKMGARNI ADLARMT