ID   DCUA_SERMA              Reviewed;         132 AA.
AC   P40684;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=Anaerobic C4-dicarboxylate transporter DcuA;
DE   Flags: Fragment;
GN   Name=dcuA;
OS   Serratia marcescens.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Serratia.
OX   NCBI_TaxID=615;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Sr41;
RX   PubMed=7846149; DOI=10.1006/plas.1994.1061;
RA   Omori K., Akatsuka H., Komatsubara S.;
RT   "Construction of a versatile promoter analysis vector and its use for
RT   analysis of the Serratia marcescens aspartase promoter region.";
RL   Plasmid 32:233-237(1994).
CC   -!- FUNCTION: Responsible for the transport of C4-dicarboxylates from the
CC       periplasm across the inner membrane. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
CC       {ECO:0000305}.
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DR   EMBL; D13252; BAA20989.1; -; Genomic_DNA.
DR   PIR; PS0397; PS0397.
DR   AlphaFoldDB; P40684; -.
DR   STRING; 273526.SMDB11_4453; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015556; F:C4-dicarboxylate transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR004668; Anaer_Dcu_memb_transpt.
DR   PANTHER; PTHR36106; PTHR36106; 1.
DR   Pfam; PF03605; DcuA_DcuB; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..>132
FT                   /note="Anaerobic C4-dicarboxylate transporter DcuA"
FT                   /id="PRO_0000170352"
FT   TRANSMEM        1..18
FT                   /note="Helical"
FT                   /evidence="ECO:0000250"
FT   TOPO_DOM        19
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        20..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000250"
FT   TOPO_DOM        38..53
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        54..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000250"
FT   TOPO_DOM        72..85
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        86..103
FT                   /note="Helical"
FT                   /evidence="ECO:0000250"
FT   TOPO_DOM        104..>132
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000250"
FT   NON_TER         132
SQ   SEQUENCE   132 AA;  13663 MW;  E71C196B1058F1D7 CRC64;
     MLAVELVIVL LAIFLGARLG GIGIGFAGGL GVLALALIGV KPGNIPFDVI SIIMAVIAAI
     SAMQVAGGMD YLVQQTEKLL RKNPKHITIL APIVTYFLTI FAGTGNISLS ALPVIAEVAK
     EQGIKPCRPL ST