ID   ACT_LUMRU               Reviewed;         372 AA.
AC   P91754;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1997, sequence version 1.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Actin;
DE   Flags: Fragment;
OS   Lumbricus rubellus (Humus earthworm).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC   Oligochaeta; Crassiclitellata; Lumbricina; Lumbricidae; Lumbricinae;
OC   Lumbricus.
OX   NCBI_TaxID=35632;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Stuerzenbaum S.R., Morgan A.J., Kille P.;
RL   Submitted (NOV-1996) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR   EMBL; Y09623; CAA70836.1; -; mRNA.
DR   AlphaFoldDB; P91754; -.
DR   SMR; P91754; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding.
FT   CHAIN           <1..372
FT                   /note="Actin"
FT                   /id="PRO_0000088953"
FT   NON_TER         1
SQ   SEQUENCE   372 AA;  41323 MW;  45095CE0C4D11A64 CRC64;
     EVTALVVDNG SGMCKAGFAG DDAPRAVFPS IVGRPRHQGV MVGMGQKDSY VGDEAQSKRG
     ILTLKYPIEH GIVTNWDDME KIWHHTFYNE LRVAPEEHPV LLTEAPLNPK ANREKMTQIM
     FETFNSPAMY VAIQAVLSLY ASGRTTGIVL DSGDGVTHTV PIYEGYALPH AILRLDLAGR
     DLTDYLMKIL TERGYSFTTT AEREIVRDIK EKLCYVALDF DQEMGTAASS SSLEKSYELP
     DGQVITIGNE RFRCPESMFQ PAFLGMESAG IHETTFNSIM KCDVDIRKDL YANTVMSGGT
     TMFPGIADRM QKEITSMAPS GMKIKIIAPP ERKYSVWIGG SILASLSTFQ QMWISKQEYD
     ESGPSIVHRK CF