ID   ACT_PHARH               Reviewed;         375 AA.
AC   P53689;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-AUG-2022, entry version 67.
DE   RecName: Full=Actin;
OS   Phaffia rhodozyma (Yeast) (Xanthophyllomyces dendrorhous).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC   Cystofilobasidiales; Mrakiaceae; Phaffia.
OX   NCBI_TaxID=264483;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 96594 / BCRC 22365 / CBS 6938 / JCM 9684 / VKM Y-2793;
RX   PubMed=8810038;
RX   DOI=10.1002/(sici)1097-0061(19960615)12:7<641::aid-yea952>3.0.co;2-2;
RA   Wery J., Dalderup M.J.M., Ter Linde J., van Ooyen A.J.J.;
RT   "Structural and phylogenetic analysis of the actin gene from the yeast
RT   Phaffia rhodozyma.";
RL   Yeast 12:641-651(1996).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR   EMBL; X89898; CAA61986.1; -; Genomic_DNA.
DR   PIR; S70377; S70377.
DR   AlphaFoldDB; P53689; -.
DR   SMR; P53689; -.
DR   PRIDE; P53689; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding.
FT   CHAIN           1..375
FT                   /note="Actin"
FT                   /id="PRO_0000088986"
SQ   SEQUENCE   375 AA;  41623 MW;  A5BD6C1A0357B010 CRC64;
     MDDEVAALVI DNGSGMCKAG FAGDDAPRAV FPSIVGRPRH QGVMVGMGQK DSYVGDEAQS
     KRGILTLKYP IEHGIVTNWD DMEKIWHHTF YNELRVAPEE HPVLLTEAPL NPKANREKMT
     QIMFETFNAP AFYVAIQAVL SLYASGRTTG IVLDSGDGVS HTVPIYEGFA LPHAILRLDL
     AGRDLTGYLV KCLMERGYPF TTTAEREIVR DIKEKLCYVA LDFEQEMQTA AQSSQLEKSY
     ELPDGQVITI GNERFRCPEA LFQPSFLGLE AAGIHETTYN SIMKCDLDIR KDLYGNVVLS
     GGTTMYSGIA DRMQKEITSL APSSMKVKIV APPERKYSVW IGGSILASLS TFQSMWISKQ
     EYDEAGPSIV HRKCF