ID   ACT_PHYME               Reviewed;         375 AA.
AC   P13363;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1990, sequence version 1.
DT   03-AUG-2022, entry version 71.
DE   RecName: Full=Actin;
OS   Phytophthora megasperma (Potato pink rot fungus).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=4788;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Glycinea race 1;
RX   PubMed=2102822; DOI=10.1007/bf00028777;
RA   Dudler R.;
RT   "The single-copy actin gene of Phytophthora megasperma encodes a protein
RT   considerably diverged from any other known actin.";
RL   Plant Mol. Biol. 14:415-422(1990).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR   EMBL; X15900; CAA33907.1; -; Genomic_DNA.
DR   PIR; S14894; ATJN.
DR   AlphaFoldDB; P13363; -.
DR   SMR; P13363; -.
DR   PRIDE; P13363; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding.
FT   CHAIN           1..375
FT                   /note="Actin"
FT                   /id="PRO_0000088987"
SQ   SEQUENCE   375 AA;  41988 MW;  E3F42876ED429F6A CRC64;
     MEDDIQAVVI DNGSGMCKAG FAGDDAPRAV FPSIVGMPKH LGIMVGMNQK DAYIGDEAQA
     KRGVLTLRYP IEHGIVTNWD DMEKIWSHTF YNELRVAPEE HPVLLTEAPL NPKANRERMT
     QIMFETFNVP AMYVNIQAVL SLYASGRTTG CVLDSGDGVS HTVPIYEGYA LPHAIVRLDL
     AGRDLTDYMM KILTERGYSF TTTAEREIVR DIKEKLTYVA MNFDEEMEKA ARSSTLDKSY
     ELPDGNVIVI GNERFRTPEV LFKPSMIGRE CTGVHECAFQ TIMKCDVDIR RDLYNNVVLS
     GGSTMFPGIG DRMTKEMTKL APTAMKVKII TPPERKYSVW IGGSILASLA TFQHMWISKT
     DYDESGPSIV HRKCF