ACT_PICGU
ID ACT_PICGU Reviewed; 360 AA.
AC A5DQP9; Q0ZIE9; Q6H196; Q6JEI6; Q6JEI7; Q7LLJ7; Q7Z9A4; Q7Z9B7; Q7Z9G3;
AC Q9P337;
DT 24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 12-JUN-2007, sequence version 1.
DT 25-MAY-2022, entry version 62.
DE RecName: Full=Actin;
GN Name=ACT1; ORFNames=PGUG_05600;
OS Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539
OS / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Meyerozyma.
OX NCBI_TaxID=294746;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324;
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA Birren B.W., Kellis M., Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 18-343.
RC STRAIN=ATCC 46036 / CBS 2030 / IFO 10106 / NRRL Y-2075, and
RC ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324;
RX PubMed=11491363; DOI=10.1099/00207713-51-4-1593;
RA Daniel H.-M., Sorrell T.C., Meyer W.;
RT "Partial sequence analysis of the actin gene and its potential for studying
RT the phylogeny of Candida species and their teleomorphs.";
RL Int. J. Syst. Evol. Microbiol. 51:1593-1606(2001).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 18-343.
RC STRAIN=ATCC 28873 / CBS 5265 / NRRL Y-17844, and
RC ATCC 58070 / CBS 2031 / IFO 10107 / NRRL Y-2076;
RX PubMed=12892922; DOI=10.1016/s0168-1605(03)00248-4;
RA Daniel H.-M., Meyer W.;
RT "Evaluation of ribosomal RNA and actin gene sequences for the
RT identification of ascomycetous yeasts.";
RL Int. J. Food Microbiol. 86:61-78(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 67-229.
RC STRAIN=ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324,
RC MMRL 1635, MMRL 1636, and MMRL 1759;
RX PubMed=15583292; DOI=10.1128/jcm.42.12.5624-5635.2004;
RA Diezmann S., Cox C.J., Schoenian G., Vilgalys R.J., Mitchell T.G.;
RT "Phylogeny and evolution of medical species of Candida and related taxa: a
RT multigenic analysis.";
RL J. Clin. Microbiol. 42:5624-5635(2004).
CC -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC various types of cell motility and are ubiquitously expressed in all
CC eukaryotic cells.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR EMBL; CH408161; EDK41502.1; -; Genomic_DNA.
DR EMBL; AJ389063; CAC00703.2; -; Genomic_DNA.
DR EMBL; AJ389064; CAC00704.2; -; Genomic_DNA.
DR EMBL; AJ508469; CAD48340.1; -; Genomic_DNA.
DR EMBL; AJ508515; CAD48386.1; -; Genomic_DNA.
DR EMBL; AJ508528; CAD48399.1; -; Genomic_DNA.
DR EMBL; AY497592; AAT12519.1; -; Genomic_DNA.
DR EMBL; AY497593; AAT12520.1; -; Genomic_DNA.
DR EMBL; AY497594; AAT47719.1; -; Genomic_DNA.
DR EMBL; DQ447210; ABE27291.1; -; Genomic_DNA.
DR RefSeq; XP_001482580.1; XM_001482530.1.
DR AlphaFoldDB; A5DQP9; -.
DR SMR; A5DQP9; -.
DR STRING; 4929.XP_001482580.1; -.
DR PRIDE; A5DQP9; -.
DR EnsemblFungi; EDK41502; EDK41502; PGUG_05600.
DR GeneID; 5124165; -.
DR KEGG; pgu:PGUG_05600; -.
DR eggNOG; KOG0676; Eukaryota.
DR HOGENOM; CLU_027965_0_2_1; -.
DR InParanoid; A5DQP9; -.
DR OMA; FHTTAER; -.
DR OrthoDB; 649708at2759; -.
DR Proteomes; UP000001997; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR InterPro; IPR004000; Actin.
DR InterPro; IPR020902; Actin/actin-like_CS.
DR InterPro; IPR004001; Actin_CS.
DR InterPro; IPR043129; ATPase_NBD.
DR PANTHER; PTHR11937; PTHR11937; 1.
DR Pfam; PF00022; Actin; 1.
DR PRINTS; PR00190; ACTIN.
DR SMART; SM00268; ACTIN; 1.
DR SUPFAM; SSF53067; SSF53067; 2.
DR PROSITE; PS00406; ACTINS_1; 1.
DR PROSITE; PS00432; ACTINS_2; 1.
DR PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding;
KW Reference proteome.
FT CHAIN 1..360
FT /note="Actin"
FT /id="PRO_0000295033"
SQ SEQUENCE 360 AA; 40371 MW; 56B9288AC3503E9E CRC64;
MCKAGFAGDD APRAVFPSIV GRPRHQGIMV GMGQRDSYVG DEAQSKRGIL TLRYPIEHGI
VKNWDDMEKI WHHTFYNELR VAPEEHPVLL TEAPMNPKLN REKMTQIMFE TFNVPAFYVN
IQAVLSLYSS GRTTGIVLDS GDGVTHVVPI YAGFSLPHGI LRLDLAGRDL TDYLMKILSE
RGYTFTTTAE REIVRDIKEK LCYVALDFEQ EMQTSSQSSA IEKSYELPDG QVITIGNERF
RAVEALFRPS DLGLEAAGID QTTYNSIIKC DLDVRKELYG NIVMSGGTTM FPGIAERMQK
EITALAPSSM KVKIIAPPER KYSVWIGGSI LASLSTFQQM WISKQEYDES GPSIVHHKCF
