ID   ACT_PROCL               Reviewed;         322 AA.
AC   P45521;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Actin;
DE   Flags: Fragment;
OS   Procambarus clarkii (Red swamp crayfish).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Multicrustacea;
OC   Malacostraca; Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Astacidea;
OC   Astacoidea; Cambaridae; Procambarus.
OX   NCBI_TaxID=6728;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Muscle;
RX   PubMed=8224920; DOI=10.1016/0378-1119(93)90657-o;
RA   Kang W., Naya Y.;
RT   "Sequence of the cDNA encoding an actin homolog in the crayfish Procambarus
RT   clarkii.";
RL   Gene 133:303-304(1993).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells.
CC   -!- INTERACTION:
CC       P45521; Q91CG6: env; Xeno; NbExp=2; IntAct=EBI-875537, EBI-875529;
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAA03463.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; D14612; BAA03463.1; ALT_INIT; mRNA.
DR   PIR; JC2008; JC2008.
DR   AlphaFoldDB; P45521; -.
DR   SMR; P45521; -.
DR   IntAct; P45521; 1.
DR   PRIDE; P45521; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   1: Evidence at protein level;
KW   ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding.
FT   CHAIN           <1..322
FT                   /note="Actin"
FT                   /id="PRO_0000088999"
FT   NON_TER         1
SQ   SEQUENCE   322 AA;  36124 MW;  C289990DBAC1197E CRC64;
     VGDEAQSKRG ILTLKYPIEH GIITNWDDME KIWYHTFYNE LRIAPEESPT MLTEAPLNPK
     ANREKMTQIM FEAFNLPATY VTIQAVLSLY ASGRTTGLVC DSGDGVSHMV PVYEGFALPH
     AILRLDLAGR DLTNYLMKIM TERGYSFTTT AEREIVRDIK EKLCYIALDF ENEMNVSAAS
     SSIDKSYELP DGQVITIGNE RFRCPEALFQ PSFLGMESVG VHETVHSSIM RCDIDIRKDL
     FANIVVSGGT TMYPGIADRL QKEITALAPA TIKIKIIAPP ERKYSVWIGG SILASLSTFQ
     TMWITKEEYD ESGPGIVHRK CF