ID   ACT_STECV               Reviewed;         375 AA.
AC   O00937;
DT   19-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1999, sequence version 2.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Actin;
OS   Sterkiella cavicola (Ciliate) (Histriculus cavicola).
OC   Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
OC   Stichotrichia; Sporadotrichida; Oxytrichidae; Stylonychinae; Sterkiella.
OX   NCBI_TaxID=742176;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=10519214; DOI=10.1111/j.1550-7408.1999.tb06063.x;
RA   Perez-Romero P., Villalobo E., Diaz-Ramos C., Calvo P., Torres A.;
RT   "Actin of Histriculus cavicola: characteristics of the highly divergent
RT   hypotrich ciliate actins.";
RL   J. Eukaryot. Microbiol. 46:469-472(1999).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR   EMBL; Y12047; CAA72778.1; -; Genomic_DNA.
DR   AlphaFoldDB; O00937; -.
DR   SMR; O00937; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding.
FT   CHAIN           1..375
FT                   /note="Actin"
FT                   /id="PRO_0000088949"
SQ   SEQUENCE   375 AA;  41853 MW;  EAA9A2EA82316BDC CRC64;
     MSEQQTCVID NGSGVVKAGF SGEDAPRAVY PSIVGRPKNV SALIGVDSAS EYLGDEAQQK
     RGVLKIFYPI EHGIVKDWDD MEKIWNHTFY VELRVSPDEH PVLLTEAPLN PKVNREKMTQ
     IMFETFNVPA LYVAIQAVLS LYSAGRTTGI VCDAGDGVTH TVPIYEGFSI PHAVSRIQLA
     GRDLTTFMAK LLTERGYSFT SSAELEIVRD IKEKLCFVAL DYEAALKQSH DSSTFEKNYE
     LPDGKIITIG SERFRCPEYL FKPLEMNGKE LDSIQDLTYK SIQECDVDVR RDLYQTIILS
     GGSTSIEGIG ERLLKEIENR APKSINVKVI ASPDRRFAVW RGGSTLTSLS TFASMWITKE
     DYDENGASIV HRKCI