ID   ACT_YARLI               Reviewed;         375 AA.
AC   Q9UVF3; Q6C9U6;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 2.
DT   25-MAY-2022, entry version 106.
DE   RecName: Full=Actin;
GN   Name=ACT1; OrderedLocusNames=YALI0D08272g;
OS   Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Dipodascaceae; Yarrowia.
OX   NCBI_TaxID=284591;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Blanchin-Roland S., Lepingle A., Benetti P.H., Gaillardin C.;
RT   "Cloning and characterization of the actin gene from Yarrowia lipolytica.";
RL   Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CLIB 122 / E 150;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR   EMBL; AJ250347; CAB62086.1; -; Genomic_DNA.
DR   EMBL; CR382130; CAG80754.2; -; Genomic_DNA.
DR   RefSeq; XP_502566.2; XM_502566.2.
DR   AlphaFoldDB; Q9UVF3; -.
DR   SMR; Q9UVF3; -.
DR   STRING; 4952.CAG80754; -.
DR   PRIDE; Q9UVF3; -.
DR   EnsemblFungi; CAG80754; CAG80754; YALI0_D08272g.
DR   GeneID; 2911067; -.
DR   KEGG; yli:YALI0D08272g; -.
DR   VEuPathDB; FungiDB:YALI0_D08272g; -.
DR   HOGENOM; CLU_027965_0_2_1; -.
DR   InParanoid; Q9UVF3; -.
DR   OMA; FHTTAER; -.
DR   Proteomes; UP000001300; Chromosome D.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding;
KW   Reference proteome.
FT   CHAIN           1..375
FT                   /note="Actin"
FT                   /id="PRO_0000089050"
FT   CONFLICT        108
FT                   /note="A -> G (in Ref. 1; CAB62086)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   375 AA;  41800 MW;  D3576B6AAF6DEEDD CRC64;
     MEDETVALVI DNGSGMCKAG FAGDDAPRAV FPSIVGRPRH QGVMVGMGQK DSYVGDEAQS
     KRGILTLRYP IEHGIVTNWD DMEKIWHHTF YNELRVAPEE HPVLLTEAPI NPKSNREKMT
     QIFFETFNAP AFYVSIQAVL SLYASGRVTG IVLDSGDGVT HVVPIYSGFS LPHAIMRLDM
     AGRDLTDYLM KILSERGYSF TNSAEREIVR DIKEKLCYVA LDFEQELQTA SQSSSLEKSY
     ELPDGRVITI GNERFRAPEA LFHPSMLGLE AAGIHETTFN SIMKCDVDVR KDLYGNIVMS
     GGTTMYPGIA ERMHKEISAL APTSIKVKIT APLERKYSVW IGGSILASLG TFQQMWISKQ
     EYDEAGPTIV HRKCY