ID   ACUB_BACSU              Reviewed;         214 AA.
AC   P39066;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   03-AUG-2022, entry version 123.
DE   RecName: Full=Acetoin utilization protein AcuB;
GN   Name=acuB; OrderedLocusNames=BSU29700;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=7934817; DOI=10.1111/j.1365-2958.1993.tb01952.x;
RA   Grundy F.J., Waters D.A., Takova T.Y., Henkin T.M.;
RT   "Identification of genes involved in utilization of acetate and acetoin in
RT   Bacillus subtilis.";
RL   Mol. Microbiol. 10:259-271(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9387221; DOI=10.1099/00221287-143-11-3431;
RA   Lapidus A., Galleron N., Sorokin A., Ehrlich S.D.;
RT   "Sequencing and functional annotation of the Bacillus subtilis genes in the
RT   200 kb rrnB-dnaB region.";
RL   Microbiology 143:3431-3441(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
CC   -!- FUNCTION: Role in growth and sporulation on acetoin or butanediol.
CC       Involved in the breakdown of these compounds used as a carbon source.
CC   -!- PATHWAY: Ketone degradation; acetoin degradation.
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DR   EMBL; L17309; AAA68285.1; -; Genomic_DNA.
DR   EMBL; AF008220; AAC00395.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB14948.1; -; Genomic_DNA.
DR   PIR; S39644; S39644.
DR   RefSeq; NP_390848.1; NC_000964.3.
DR   RefSeq; WP_003229294.1; NZ_JNCM01000036.1.
DR   AlphaFoldDB; P39066; -.
DR   SMR; P39066; -.
DR   DIP; DIP-61108N; -.
DR   IntAct; P39066; 1.
DR   STRING; 224308.BSU29700; -.
DR   PaxDb; P39066; -.
DR   PRIDE; P39066; -.
DR   EnsemblBacteria; CAB14948; CAB14948; BSU_29700.
DR   GeneID; 937318; -.
DR   KEGG; bsu:BSU29700; -.
DR   PATRIC; fig|224308.179.peg.3228; -.
DR   eggNOG; COG0517; Bacteria.
DR   InParanoid; P39066; -.
DR   OMA; CAHPLDF; -.
DR   PhylomeDB; P39066; -.
DR   BioCyc; BSUB:BSU29700-MON; -.
DR   UniPathway; UPA00040; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0045150; P:acetoin catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR   Gene3D; 3.10.580.10; -; 1.
DR   InterPro; IPR000644; CBS_dom.
DR   InterPro; IPR046342; CBS_dom_sf.
DR   Pfam; PF00571; CBS; 2.
DR   SMART; SM00116; CBS; 2.
DR   SUPFAM; SSF54631; SSF54631; 1.
DR   PROSITE; PS51371; CBS; 2.
PE   4: Predicted;
KW   Acetoin catabolism; CBS domain; Reference proteome; Repeat; Sporulation.
FT   CHAIN           1..214
FT                   /note="Acetoin utilization protein AcuB"
FT                   /id="PRO_0000064446"
FT   DOMAIN          7..66
FT                   /note="CBS 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT   DOMAIN          78..135
FT                   /note="CBS 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
SQ   SEQUENCE   214 AA;  24352 MW;  3B7A964B5C95CCEF CRC64;
     MIVEQIMKRD VITLTKTDTL ETAICKLKEF HIRHLPVVDE ERHVIGMITD RDMKQASPSI
     FEENKRSLFL TRSVDSIMKK DVVCAHPLDF VEEISAVFYE HGIGCLPVVH HQKLIGILTK
     TDLLRTFVKL TGADQPGSQI EIKVNDITKS LAEISSLCQD LQVKILSVLV YPHDDPGVKV
     LVFRVKTMNP LPFLQALQRN GHHVVWPSEQ RDLL