ID   ACUC_STAAM              Reviewed;         389 AA.
AC   P64375; Q99TC9;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=Acetoin utilization protein AcuC;
GN   Name=acuC; OrderedLocusNames=SAV1735;
OS   Staphylococcus aureus (strain Mu50 / ATCC 700699).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=158878;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Mu50 / ATCC 700699;
RX   PubMed=11418146; DOI=10.1016/s0140-6736(00)04403-2;
RA   Kuroda M., Ohta T., Uchiyama I., Baba T., Yuzawa H., Kobayashi I., Cui L.,
RA   Oguchi A., Aoki K., Nagai Y., Lian J.-Q., Ito T., Kanamori M.,
RA   Matsumaru H., Maruyama A., Murakami H., Hosoyama A., Mizutani-Ui Y.,
RA   Takahashi N.K., Sawano T., Inoue R., Kaito C., Sekimizu K., Hirakawa H.,
RA   Kuhara S., Goto S., Yabuzaki J., Kanehisa M., Yamashita A., Oshima K.,
RA   Furuya K., Yoshino C., Shiba T., Hattori M., Ogasawara N., Hayashi H.,
RA   Hiramatsu K.;
RT   "Whole genome sequencing of meticillin-resistant Staphylococcus aureus.";
RL   Lancet 357:1225-1240(2001).
CC   -!- FUNCTION: Role in growth on acetoin or butanediol. Involved in the
CC       breakdown of these compounds used as a carbon source (By similarity).
CC       {ECO:0000250}.
CC   -!- PATHWAY: Ketone degradation; acetoin degradation.
CC   -!- SIMILARITY: Belongs to the histone deacetylase family. {ECO:0000305}.
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DR   EMBL; BA000017; BAB57897.1; -; Genomic_DNA.
DR   RefSeq; WP_001184011.1; NC_002758.2.
DR   AlphaFoldDB; P64375; -.
DR   SMR; P64375; -.
DR   PaxDb; P64375; -.
DR   EnsemblBacteria; BAB57897; BAB57897; SAV1735.
DR   KEGG; sav:SAV1735; -.
DR   HOGENOM; CLU_007727_8_0_9; -.
DR   OMA; GWLRAFH; -.
DR   PhylomeDB; P64375; -.
DR   BioCyc; SAUR158878:SAV_RS09325-MON; -.
DR   UniPathway; UPA00040; -.
DR   Proteomes; UP000002481; Chromosome.
DR   GO; GO:0045150; P:acetoin catabolic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd09994; HDAC_AcuC_like; 1.
DR   Gene3D; 3.40.800.20; -; 1.
DR   InterPro; IPR003085; AcuC.
DR   InterPro; IPR000286; His_deacetylse.
DR   InterPro; IPR023801; His_deacetylse_dom.
DR   InterPro; IPR037138; His_deacetylse_dom_sf.
DR   InterPro; IPR023696; Ureohydrolase_dom_sf.
DR   Pfam; PF00850; Hist_deacetyl; 1.
DR   PRINTS; PR01272; ACUCPROTEIN.
DR   PRINTS; PR01270; HDASUPER.
DR   SUPFAM; SSF52768; SSF52768; 1.
PE   3: Inferred from homology;
KW   Acetoin catabolism.
FT   CHAIN           1..389
FT                   /note="Acetoin utilization protein AcuC"
FT                   /id="PRO_0000114731"
SQ   SEQUENCE   389 AA;  44571 MW;  CA59920FC2893BFE CRC64;
     MQQHSSKTAY VYSDKLLQYR FHDQHPFNQM RLKLTTELLL NANLLSPEQI VQPRIATGDE
     LMLIHKYDYV EAIKHASHGI ISEDEAKKYG LNDEENGQFK HMHRHSATIV GGALTLADLI
     MSGKVLNGCH LGGGLHHAQP GRASGFCIYN DIAITAQYIA KEYNQRVLII DTDAHHGDGT
     QWSFYADNHV TTYSIHETGK FLFPGSGHYT ERGEDIGYGH TVNVPLEPYT EDASFLECFK
     LTVEPVVKSF KPDIILSVNG VDIHYRDPLT HLNCTLHSLY EIPYFVKYLA DSYTNGKVIM
     FGGGGYNIWR VVPRAWSHVF LSLIDQPIQS GYLPLEWINK WKHYSSELLP KRWEDRLNDY
     TYVPRTKEIS EKNKKLALHI ASWYESTRQ