ID   ACUK_ARTBC              Reviewed;         721 AA.
AC   D4AL61;
DT   05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT   18-MAY-2010, sequence version 1.
DT   25-MAY-2022, entry version 54.
DE   RecName: Full=Transcription activator of gluconeogenesis ARB_05058;
GN   ORFNames=ARB_05058;
OS   Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton
OS   mentagrophytes).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX   NCBI_TaxID=663331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4681 / CBS 112371;
RX   PubMed=21247460; DOI=10.1186/gb-2011-12-1-r7;
RA   Burmester A., Shelest E., Gloeckner G., Heddergott C., Schindler S.,
RA   Staib P., Heidel A., Felder M., Petzold A., Szafranski K., Feuermann M.,
RA   Pedruzzi I., Priebe S., Groth M., Winkler R., Li W., Kniemeyer O.,
RA   Schroeckh V., Hertweck C., Hube B., White T.C., Platzer M., Guthke R.,
RA   Heitman J., Woestemeyer J., Zipfel P.F., Monod M., Brakhage A.A.;
RT   "Comparative and functional genomics provide insights into the
RT   pathogenicity of dermatophytic fungi.";
RL   Genome Biol. 12:R7.1-R7.16(2011).
CC   -!- FUNCTION: Transcription factor which regulates nonfermentable carbon
CC       utilization. Activator of gluconeogenetic genes (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00227}.
CC   -!- SIMILARITY: Belongs to the ERT1/acuK family. {ECO:0000305}.
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DR   EMBL; ABSU01000002; EFE36120.1; -; Genomic_DNA.
DR   RefSeq; XP_003016765.1; XM_003016719.1.
DR   AlphaFoldDB; D4AL61; -.
DR   SMR; D4AL61; -.
DR   STRING; 663331.D4AL61; -.
DR   EnsemblFungi; EFE36120; EFE36120; ARB_05058.
DR   GeneID; 9522251; -.
DR   KEGG; abe:ARB_05058; -.
DR   eggNOG; ENOG502R1M5; Eukaryota.
DR   HOGENOM; CLU_010748_1_0_1; -.
DR   OMA; VMTTCKL; -.
DR   Proteomes; UP000008866; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
DR   CDD; cd00067; GAL4; 1.
DR   InterPro; IPR001138; Zn2-C6_fun-type_DNA-bd.
DR   InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR   SMART; SM00066; GAL4; 1.
DR   SUPFAM; SSF57701; SSF57701; 1.
DR   PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Gluconeogenesis; Metal-binding; Nucleus;
KW   Reference proteome; Transcription; Transcription regulation; Zinc.
FT   CHAIN           1..721
FT                   /note="Transcription activator of gluconeogenesis
FT                   ARB_05058"
FT                   /id="PRO_0000406428"
FT   DNA_BIND        65..93
FT                   /note="Zn(2)-C6 fungal-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00227"
FT   REGION          1..62
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          128..224
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          263..300
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          353..400
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          533..567
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          635..666
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..42
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        128..219
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        266..300
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        534..567
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        639..661
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   721 AA;  77819 MW;  9D25455FCB772FD6 CRC64;
     MSPHQTTGQE SDNMTVNGEN AQASSQYIQS NEEMTSAIAT EKKASTAKAA KDPSRPKRKK
     AKRACYACQR GHLTCGDERP CQRCIKRGFQ DACHDGVRKK AKYLHDAPNE ALMAGVGATL
     YNQRNAAQNN ANGSNTSPGA PQQITSPNFY NTQQSPDYNG FPQNKTELQD STVGPDNYAS
     QSPVSPTYQI SQGLSTQGLS PSLPQSTSET PSAANPAPGQ FNSAFFDPSD PALFNFDLAS
     MNFGNHYGAL EFGMLGHMAT GVGDTPPSES GAQRGSIGQN GSGTFGLTGS NFSESPSNQA
     PYLFSESGMN DWTQTAPVNR RSMYGSNANL VAGNMSDKPH AFAIESAPAN FASPASNESP
     MMTTSSATFE DTTNSGAFNS RQNVPVSQQR QQPVVSTPQL KQQNLNLGSR RRHKNASSIY
     DSVKDPYSYT SGFHSLTAFI QRRFSPQKTL RIAKALASIR PSFIATTKTL NRDDLIFMEK
     CFQRTLWEYE DFINACGTPT IVCRRTGEIA AVGKEFSILT GWKKEVLLGK EPNHNVNTGG
     SSGLMTGSTS RGSYTPRPYS SEVYNSSATA TPRTQPVFLA ELLDDDSVIE FYEDFAKLAF
     GDSRGSVMTT CKLLKYKTKA ESDILAGSNG EADAGLNGEA ASNETNELNG SLTNGATTNG
     RGQRRWGKGE IAGEAGMNQL GFRDGKVECS YCWTVKRDVF DIPMLIVMNV SCLCLEPLSE
     P