ID   DDA1_CHICK              Reviewed;         102 AA.
AC   Q5ZK14;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=DET1- and DDB1-associated protein 1 {ECO:0000250|UniProtKB:Q9BW61};
GN   Name=DDA1 {ECO:0000250|UniProtKB:Q9BW61};
GN   ORFNames=RCJMB04_13o6 {ECO:0000303|PubMed:15642098};
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: Functions as a component of numerous distinct DCX (DDB1-CUL4-
CC       X-box) E3 ubiquitin-protein ligase complexes which mediate the
CC       ubiquitination and subsequent proteasomal degradation of target
CC       proteins. In the DCX complexes, acts as a scaffolding subunit required
CC       to stabilize the complex. {ECO:0000250|UniProtKB:Q9BW61}.
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC       {ECO:0000250|UniProtKB:Q9BW61}.
CC   -!- SUBUNIT: Component of numerous DCX (DDB1-CUL4-X-box) E3 ubiquitin-
CC       protein ligase complexes which consist of a core of DDB1, cullin-4
CC       (CUL4A or CUL4B), DDA1 and RBX1. {ECO:0000250|UniProtKB:Q9BW61}.
CC   -!- SIMILARITY: Belongs to the DDA1 family. {ECO:0000305}.
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DR   EMBL; AJ720270; CAG31929.1; -; mRNA.
DR   RefSeq; NP_001026579.1; NM_001031408.1.
DR   AlphaFoldDB; Q5ZK14; -.
DR   SMR; Q5ZK14; -.
DR   STRING; 9031.ENSGALP00000001589; -.
DR   PaxDb; Q5ZK14; -.
DR   PRIDE; Q5ZK14; -.
DR   GeneID; 426942; -.
DR   KEGG; gga:426942; -.
DR   CTD; 79016; -.
DR   VEuPathDB; HostDB:geneid_426942; -.
DR   eggNOG; KOG4816; Eukaryota.
DR   HOGENOM; CLU_144562_1_0_1; -.
DR   InParanoid; Q5ZK14; -.
DR   OrthoDB; 1521756at2759; -.
DR   PhylomeDB; Q5ZK14; -.
DR   TreeFam; TF323534; -.
DR   UniPathway; UPA00143; -.
DR   PRO; PR:Q5ZK14; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0080008; C:Cul4-RING E3 ubiquitin ligase complex; ISS:UniProtKB.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR   GO; GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.
DR   InterPro; IPR033575; DDA1.
DR   InterPro; IPR018276; DDA1_N.
DR   PANTHER; PTHR31879; PTHR31879; 1.
DR   Pfam; PF10172; DDA1; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Ubl conjugation pathway.
FT   CHAIN           1..102
FT                   /note="DET1- and DDB1-associated protein 1"
FT                   /id="PRO_0000310273"
FT   REGION          67..102
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   102 AA;  11884 MW;  64B13C254ACB9EB7 CRC64;
     MADFLKGLPV YNKSNFSRFH ADSVCKASNR RPSVYLPTRE YPSEQIIVTE KTNILLRYLH
     QQWDKKNAAK KRDQEQVEIE GENSAPPRKI ARTDSQDMNE DT