ID   DDB1_SOLCE              Reviewed;        1095 AA.
AC   Q6E7D1;
DT   23-NOV-2004, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=DNA damage-binding protein 1;
DE   AltName: Full=UV-damaged DNA-binding protein 1;
GN   Name=DDB1;
OS   Solanum cheesmaniae (Galapagos Island tomato) (Lycopersicon cheesmaniae).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC   Solanum subgen. Lycopersicon.
OX   NCBI_TaxID=142759;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=15178762; DOI=10.1073/pnas.0400935101;
RA   Liu Y., Roof S., Ye Z., Barry C., van Tuinen A., Vrebalov J., Bowler C.,
RA   Giovannoni J.;
RT   "Manipulation of light signal transduction as a means of modifying fruit
RT   nutritional quality in tomato.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:9897-9902(2004).
CC   -!- FUNCTION: Component of light signal transduction machinery. Involved in
CC       fruit pigmentation and fruit nutritional quality. Acts as a negative
CC       regulator of fruit pigmentation. Probably acts by participating in the
CC       CDD complex, a complex probably required to regulate the activity of
CC       ubiquitin conjugating enzymes. Repression of photomorphogenesis is
CC       probably mediated by ubiquitination and subsequent degradation of
CC       photomorphogenesis-promoting factors such as HY5 (By similarity).
CC       {ECO:0000250}.
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC   -!- SUBUNIT: Probable component of the CDD complex, which probably also
CC       contains DET1. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the DDB1 family. {ECO:0000305}.
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DR   EMBL; AY531661; AAT66742.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q6E7D1; -.
DR   SMR; Q6E7D1; -.
DR   UniPathway; UPA00143; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0009585; P:red, far-red light phototransduction; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; -; 3.
DR   InterPro; IPR004871; Cleavage/polyA-sp_fac_asu_C.
DR   InterPro; IPR018846; Cleavage/polyA-sp_fac_asu_N.
DR   InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   Pfam; PF03178; CPSF_A; 1.
DR   Pfam; PF10433; MMS1_N; 1.
DR   SUPFAM; SSF50998; SSF50998; 1.
PE   3: Inferred from homology;
KW   Nucleus; Phytochrome signaling pathway.
FT   CHAIN           1..1095
FT                   /note="DNA damage-binding protein 1"
FT                   /id="PRO_0000079841"
SQ   SEQUENCE   1095 AA;  122293 MW;  F3C10878D7D26772 CRC64;
     MSVWNYVVTA HKPTNVTHSC VGNFTGPQEL NLIIAKCTRI EIHLLTPQGL QCICLQPMLD
     VPIYGRIATL ELFRPHGETQ DLLFIATERY KFCVLQWDTE ASEVITRAMG DVSDRIGRPT
     DNGQIGIIDP DCRLIGLHLY DGLFKVIPFD NKGQLKEAFN IRLEELQVLD IKFLYGCPKP
     TIVVLYQDNK DARHVKTYEV SLKDKDFIEG PWAQNNLDNG ASLLIPVPPP LCGVLIIGEE
     TIVYCSASAF KAIPIRPSIT RAYGRVDADG SRYLLGDHNG LLHLLVITHE KEKVTGLKIE
     LLGETSIAST ISYLDNAFVF IGSSYGDSQL VKLNLQPDTK GSYVEVLERY VNLGPIVDFC
     VVDLERQGQG QVVTCSGAYK DGSLRIVRNG IGINEQASVE LQGIKGMWSL RSATDDPYDT
     FLVVSFISET RVLAMNLEDE LEETEIEGFN SQVQTLFCHD AVYNQLVQVT SNSVRLVSST
     SRDLKNEWFA PVGYSVNVAT ANATQVLLAT GGGHLVYLEI GDGVLNEVKY AKLDYDISCL
     DINPIGENPN YSNIAAVGMW TDISVRIYSL PDLNLITKEQ LGGEIIPRSV LMCSFEGISY
     LLCALGDGHL LNFVLSMSTG ELTDRKKVSL GTQPITLRTF SSKDTTHVFA ASDRPTVIYS
     SNKKLLYSNV NLKEVSHMCP FNVAAFPDSL AIAKEGELTI GTIDEIQKLH IRSIPLGEHA
     RRISHQEQTR TFALCSVKYT QSNADDPEMH FVRLLDDQTF EFISTYPLDQ FEYGCSILSC
     SFSDDSNVYY CIGTAYVMPE ENEPTKGRIL VFIVEDGKLQ LIAEKETKGA VYSLNAFNGK
     LLAAINQKIQ LYKWASREDG GSRELQTECG HHGHILALYV QTRGDFIVVG DLMKSISLLI
     FKHEEGAIEE RARDYNANWM SAVEILDDDI YLGAENNFNL FTVRKNSEGA TDEERSRLEV
     VGEYHLGEFV NRFRHGSLVM RLPDSDVGQI PTVIFGTVNG VIGVIASLPH DQYLFLEKLQ
     TNLRKVIKGV GGLSHEQWRS FYNEKKTVDA KNFLDGDLIE SFLDLSRNRM EEISKAMSVP
     VEELMKRVEE LTRLH