ID   ACUK_FUSV7              Reviewed;         662 AA.
AC   C7YM38;
DT   05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT   13-OCT-2009, sequence version 1.
DT   25-MAY-2022, entry version 58.
DE   RecName: Full=Transcription activator of gluconeogenesis NECHADRAFT_59099;
GN   ORFNames=NECHADRAFT_59099;
OS   Fusarium vanettenii (strain ATCC MYA-4622 / CBS 123669 / FGSC 9596 / NRRL
OS   45880 / 77-13-4) (Fusarium solani subsp. pisi).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC   Fusarium solani species complex; Fusarium vanettenii.
OX   NCBI_TaxID=660122;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4622 / CBS 123669 / FGSC 9596 / NRRL 45880 / 77-13-4;
RX   PubMed=19714214; DOI=10.1371/journal.pgen.1000618;
RA   Coleman J.J., Rounsley S.D., Rodriguez-Carres M., Kuo A., Wasmann C.C.,
RA   Grimwood J., Schmutz J., Taga M., White G.J., Zhou S., Schwartz D.C.,
RA   Freitag M., Ma L.-J., Danchin E.G.J., Henrissat B., Coutinho P.M.,
RA   Nelson D.R., Straney D., Napoli C.A., Barker B.M., Gribskov M., Rep M.,
RA   Kroken S., Molnar I., Rensing C., Kennell J.C., Zamora J., Farman M.L.,
RA   Selker E.U., Salamov A., Shapiro H., Pangilinan J., Lindquist E.,
RA   Lamers C., Grigoriev I.V., Geiser D.M., Covert S.F., Temporini E.,
RA   VanEtten H.D.;
RT   "The genome of Nectria haematococca: contribution of supernumerary
RT   chromosomes to gene expansion.";
RL   PLoS Genet. 5:E1000618-E1000618(2009).
CC   -!- FUNCTION: Transcription factor which regulates nonfermentable carbon
CC       utilization. Activator of gluconeogenetic genes (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00227}.
CC   -!- SIMILARITY: Belongs to the ERT1/acuK family. {ECO:0000305}.
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DR   EMBL; GG698897; EEU47385.1; -; Genomic_DNA.
DR   RefSeq; XP_003053098.1; XM_003053052.1.
DR   AlphaFoldDB; C7YM38; -.
DR   SMR; C7YM38; -.
DR   STRING; 140110.NechaP59099; -.
DR   PRIDE; C7YM38; -.
DR   EnsemblFungi; NechaT59099; NechaP59099; NechaG59099.
DR   GeneID; 9671122; -.
DR   KEGG; nhe:NECHADRAFT_59099; -.
DR   eggNOG; ENOG502R1M5; Eukaryota.
DR   HOGENOM; CLU_010748_1_0_1; -.
DR   InParanoid; C7YM38; -.
DR   OMA; VMTTCKL; -.
DR   OrthoDB; 681770at2759; -.
DR   Proteomes; UP000005206; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
DR   CDD; cd00067; GAL4; 1.
DR   Gene3D; 4.10.240.10; -; 1.
DR   InterPro; IPR001138; Zn2-C6_fun-type_DNA-bd.
DR   InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR   SMART; SM00066; GAL4; 1.
DR   SUPFAM; SSF57701; SSF57701; 1.
DR   PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Gluconeogenesis; Metal-binding; Nucleus;
KW   Reference proteome; Transcription; Transcription regulation; Zinc.
FT   CHAIN           1..662
FT                   /note="Transcription activator of gluconeogenesis
FT                   NECHADRAFT_59099"
FT                   /id="PRO_0000406441"
FT   DOMAIN          448..519
FT                   /note="PAS"
FT   DNA_BIND        66..94
FT                   /note="Zn(2)-C6 fungal-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00227"
FT   REGION          1..61
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          105..149
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          502..524
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          580..606
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        11..25
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        26..56
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        123..149
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   662 AA;  72774 MW;  87AC80C2701926A7 CRC64;
     MPHEMEENGA EVSDVMSENE DDTETFLKDD EKMTEQSTTD STTEVKKKYD PKDPLRPRRK
     KARRACFACQ RAHLTCGDER PCQRCIKRGL ADACQDGVRK KAKYLHDAPP EALRPVLGPN
     YNPTPTPSRT NGHRHSSSQS DNLSATGSNF FSQGSTASLP VYSAGAQTPV AIDGLPSFNP
     QTSPTSFQGP INNAAHTPMN NMMPAGNMDF NALFDPSNPA LYNFDLEGLN FGSQYAGWEF
     GILNKMALGA ETPPRENSMS QTPTTEANYA ALFGNANNGF DHPMLGADFS GMDQNNQSLY
     AQGNLQHGLP HAYAIAAGPT SLASPSTDTT ASPHSVAGMD GSPNHNFAGI PTVPAATRPR
     PKHNKAGPKS ILGKRQRDSA AIYESVKEPY PYTTGFHNMV AVLRNRLPGN KLLRIAKALG
     EIRPSFISCT KDLTRQDLVF MEKCFQRTLV EYDDFLQHCC APTIVCRRSG EVAAVNKEFT
     ALTGWTKDVL LGKEPNLNVN VYSGRSTNGT NTPDHNSQGE MTTPRPQRAM LDLSGGRPQP
     VFLGELLDDD SVVEFYQDFS QLAFEDSRGK VQRSCRLNKY RAPQDPDQKE PGSQKDAQPG
     ILSSRVTRID GSHGISRIEK DGKVECTYCW TIKRDVFDIP MMIIINFLPR YLPDQGPQQL
     AV