ID   ACUK_PYRTR              Reviewed;         694 AA.
AC   B2W978;
DT   05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-2008, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=Transcription activator of gluconeogenesis PTRG_06536;
GN   ORFNames=PTRG_06536;
OS   Pyrenophora tritici-repentis (strain Pt-1C-BFP) (Wheat tan spot fungus)
OS   (Drechslera tritici-repentis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae;
OC   Pyrenophora.
OX   NCBI_TaxID=426418;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Pt-1C-BFP;
RX   PubMed=23316438; DOI=10.1534/g3.112.004044;
RA   Manning V.A., Pandelova I., Dhillon B., Wilhelm L.J., Goodwin S.B.,
RA   Berlin A.M., Figueroa M., Freitag M., Hane J.K., Henrissat B., Holman W.H.,
RA   Kodira C.D., Martin J., Oliver R.P., Robbertse B., Schackwitz W.,
RA   Schwartz D.C., Spatafora J.W., Turgeon B.G., Yandava C., Young S., Zhou S.,
RA   Zeng Q., Grigoriev I.V., Ma L.-J., Ciuffetti L.M.;
RT   "Comparative genomics of a plant-pathogenic fungus, Pyrenophora tritici-
RT   repentis, reveals transduplication and the impact of repeat elements on
RT   pathogenicity and population divergence.";
RL   G3 (Bethesda) 3:41-63(2013).
CC   -!- FUNCTION: Transcription factor which regulates nonfermentable carbon
CC       utilization. Activator of gluconeogenetic genes (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00227}.
CC   -!- SIMILARITY: Belongs to the ERT1/acuK family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DS231620; EDU49456.1; -; Genomic_DNA.
DR   RefSeq; XP_001936869.1; XM_001936834.1.
DR   AlphaFoldDB; B2W978; -.
DR   STRING; 45151.EDU49456; -.
DR   EnsemblFungi; EDU49456; EDU49456; PTRG_06536.
DR   GeneID; 6344795; -.
DR   eggNOG; ENOG502R1M5; Eukaryota.
DR   HOGENOM; CLU_010748_1_0_1; -.
DR   InParanoid; B2W978; -.
DR   OMA; VMTTCKL; -.
DR   OrthoDB; 681770at2759; -.
DR   Proteomes; UP000001471; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
DR   CDD; cd00067; GAL4; 1.
DR   Gene3D; 4.10.240.10; -; 1.
DR   InterPro; IPR001138; Zn2-C6_fun-type_DNA-bd.
DR   InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR   SMART; SM00066; GAL4; 1.
DR   SUPFAM; SSF57701; SSF57701; 1.
DR   PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Gluconeogenesis; Metal-binding; Nucleus;
KW   Reference proteome; Transcription; Transcription regulation; Zinc.
FT   CHAIN           1..694
FT                   /note="Transcription activator of gluconeogenesis
FT                   PTRG_06536"
FT                   /id="PRO_0000406450"
FT   DOMAIN          485..559
FT                   /note="PAS"
FT   DNA_BIND        64..92
FT                   /note="Zn(2)-C6 fungal-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00227"
FT   REGION          1..57
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          175..216
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          289..369
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          384..420
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          539..569
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        11..28
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        29..44
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        175..214
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        299..324
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        348..369
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        384..409
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   694 AA;  76570 MW;  8EF8E1EB19769F1F CRC64;
     MTTPDAEDAS PSPEYRSDQD DDMAAEQTTD RQSGDASPTQ KPANGKPNAK DPLRPRRKKA
     RRACFACQRA HLTCGDERPC GRCIKRGLQD HCMDGVRKKA KYLHDAPDGS LMPGVGGHYP
     YMNGNRPTPL PAQDTHTVSV SPQSNMYNQA QPPAAFYPPN SIPGQLPVTQ DTRAFSNQQS
     PISPPFTQAH HASVQNAGAP STMSQGQQGM QQFGPLFDPS DPALFNFDIS SLNFGNHYGA
     LEFGMLGHMS SGAVETPHDN NLMNNMSGSV NMYNQQVPSG YPDQNNAAAM AFGPNGLPGS
     EWQETQSRQG SMHVHTPNNT SGSGSHDHHP HRNDSLNGPH AFAIGQGPAT HSTASPASTD
     ASTYEGDNPL STAAFFANAN RPHAQRSPLV SRPQQENRPP TTALQSIHAN GIRKRQRDTK
     SVYQGITKPY DYVKGYHRLY QLIDKKYSRP WVAKAQQYLQ NYRPVLLQVR EELNRDDLIH
     QEMGLQRHLM TLQEHFAEVG TPFLICRRSG EIVGINKEFT ILTGWKRDVL LGHEPNLNVN
     LGTNRESSES DTSTQNTTPN LSAQDSEGAT PSVNIIELMD ARSALEFLQH FSELCYQDPR
     GYASQRVNML RYQTKADVDR IHNMKNASSG DAKLDPLVKM EGGAVHQGES AMQRLGAKSG
     MVDCMIWWHI KRDIFDMPVL VCMSVMPVLD KGLP