ID   3BHST_VAR67             Reviewed;          61 AA.
AC   P33794;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 1.
DT   03-AUG-2022, entry version 67.
DE   RecName: Full=Truncated 3-beta hydroxy-5-ene steroid dehydrogenase homolog;
GN   ORFNames=A50L;
OS   Variola virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox virus).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus.
OX   NCBI_TaxID=587200;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=India-1967 / Isolate Ind3;
RX   PubMed=8384129; DOI=10.1016/0014-5793(93)80041-r;
RA   Shchelkunov S.N., Blinov V.M., Sandakhchiev L.S.;
RT   "Genes of variola and vaccinia viruses necessary to overcome the host
RT   protective mechanisms.";
RL   FEBS Lett. 319:80-83(1993).
CC   -!- DOMAIN: Corresponds to the N-terminal domain of vaccinia virus 3-beta-
CC       HSD.
CC   -!- SIMILARITY: Belongs to the 3-beta-HSD family. {ECO:0000305}.
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DR   EMBL; X69198; CAA49097.1; -; Genomic_DNA.
DR   PIR; F36853; F36853.
DR   RefSeq; NP_042200.1; NC_001611.1.
DR   SMR; P33794; -.
DR   GeneID; 1486532; -.
DR   KEGG; vg:1486532; -.
DR   Proteomes; UP000002060; Genome.
DR   GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR   InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF01073; 3Beta_HSD; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..61
FT                   /note="Truncated 3-beta hydroxy-5-ene steroid dehydrogenase
FT                   homolog"
FT                   /id="PRO_0000087796"
SQ   SEQUENCE   61 AA;  6849 MW;  2563A2FAE6CCABD6 CRC64;
     MTVYAVTGGA EFLGRYIVKL LISADDVQEI RVINVVEDPQ PLVSKVKVIN YIQCDINDLI
     R