ID   DDRGK_ARATH             Reviewed;         298 AA.
AC   Q94C53; Q8LAA5; Q9T046;
DT   02-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   25-MAY-2022, entry version 114.
DE   RecName: Full=DDRGK domain-containing protein 1;
DE   Flags: Precursor;
GN   OrderedLocusNames=At4g27120; ORFNames=T24A18.70;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617198; DOI=10.1038/47134;
RA   Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA   Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA   Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA   de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA   Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA   Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA   Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA   Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA   Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA   Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA   Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA   Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA   Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA   Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA   Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA   Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA   Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA   Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA   Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA   Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA   Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA   Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA   Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA   Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA   Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA   Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA   Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA   de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA   Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA   Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA   Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA   Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA   Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA   Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA   Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA   Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA   Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA   O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA   Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA   Martienssen R., McCombie W.R.;
RT   "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL   Nature 402:769-777(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA   Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA   Feldmann K.A.;
RT   "Full-length cDNA from Arabidopsis thaliana.";
RL   Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the DDRGK1 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAB38842.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=CAB79567.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AL035680; CAB38842.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AL161566; CAB79567.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002687; AEE85303.1; -; Genomic_DNA.
DR   EMBL; CP002687; AEE85304.1; -; Genomic_DNA.
DR   EMBL; AY035174; AAK59678.1; -; mRNA.
DR   EMBL; AY113927; AAM44975.1; -; mRNA.
DR   EMBL; AY087946; AAM65494.1; -; mRNA.
DR   PIR; T06042; T06042.
DR   RefSeq; NP_567767.1; NM_118846.4.
DR   RefSeq; NP_849456.1; NM_179125.4.
DR   AlphaFoldDB; Q94C53; -.
DR   SMR; Q94C53; -.
DR   STRING; 3702.AT4G27120.1; -.
DR   iPTMnet; Q94C53; -.
DR   PaxDb; Q94C53; -.
DR   PRIDE; Q94C53; -.
DR   ProteomicsDB; 224127; -.
DR   EnsemblPlants; AT4G27120.1; AT4G27120.1; AT4G27120.
DR   EnsemblPlants; AT4G27120.2; AT4G27120.2; AT4G27120.
DR   GeneID; 828820; -.
DR   Gramene; AT4G27120.1; AT4G27120.1; AT4G27120.
DR   Gramene; AT4G27120.2; AT4G27120.2; AT4G27120.
DR   KEGG; ath:AT4G27120; -.
DR   Araport; AT4G27120; -.
DR   TAIR; locus:2136457; AT4G27120.
DR   eggNOG; KOG3054; Eukaryota.
DR   HOGENOM; CLU_059562_2_0_1; -.
DR   InParanoid; Q94C53; -.
DR   OMA; QEFIQYI; -.
DR   OrthoDB; 1553559at2759; -.
DR   PhylomeDB; Q94C53; -.
DR   PRO; PR:Q94C53; -.
DR   Proteomes; UP000006548; Chromosome 4.
DR   ExpressionAtlas; Q94C53; baseline and differential.
DR   Genevisible; Q94C53; AT.
DR   GO; GO:0005829; C:cytosol; HDA:TAIR.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR019153; DDRGK_dom-contain.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF09756; DDRGK; 1.
DR   SMART; SM01128; DDRGK; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome; Signal.
FT   SIGNAL          1..29
FT                   /evidence="ECO:0000255"
FT   CHAIN           30..298
FT                   /note="DDRGK domain-containing protein 1"
FT                   /id="PRO_0000391870"
FT   REGION          31..155
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        62..76
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        88..155
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   298 AA;  34019 MW;  CCFBDAAEFC144E3D CRC64;
     MEEIFALIVS MILIVAVIPL FFWKRRRDAR SREEVAEPPQ VQPRENVARA GGGRRMRRRP
     AASGASSSTS NVQENGSGSE DEDEDEAGGT QARASKKKEK KRQEREAQRQ AEEATRESRN
     TKQDWYAEMR RKKDEEREAE ELKLEEEEKA RQAKEEEAAA LEFDKWKGEF SVDAEGTTEE
     VQGGNQDLLS EFVEYIKKQK CVPLEDLAAE FHLRTQECIN RIASLESIGR LSGVMDDRGK
     YIYISMEEMN AVADYIKRQG RVSISHLASK SNQFIDLEPK VQHQLTEEIS GMEEISVS