DDRGK_CAEEL
ID DDRGK_CAEEL Reviewed; 302 AA.
AC P34623; H1ZUW3; Q05035;
DT 01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT 02-MAR-2010, sequence version 3.
DT 03-AUG-2022, entry version 126.
DE RecName: Full=DDRGK domain-containing protein 1 {ECO:0000305};
DE AltName: Full=Ufm-binding protein 1 {ECO:0000312|WormBase:ZK1236.7b};
DE Flags: Precursor;
GN Name=ufbp-1 {ECO:0000312|WormBase:ZK1236.7b};
GN ORFNames=ZK1236.7 {ECO:0000312|WormBase:ZK1236.7b};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=7906398; DOI=10.1038/368032a0;
RA Wilson R., Ainscough R., Anderson K., Baynes C., Berks M., Bonfield J.,
RA Burton J., Connell M., Copsey T., Cooper J., Coulson A., Craxton M.,
RA Dear S., Du Z., Durbin R., Favello A., Fraser A., Fulton L., Gardner A.,
RA Green P., Hawkins T., Hillier L., Jier M., Johnston L., Jones M.,
RA Kershaw J., Kirsten J., Laisster N., Latreille P., Lightning J., Lloyd C.,
RA Mortimore B., O'Callaghan M., Parsons J., Percy C., Rifken L., Roopra A.,
RA Saunders D., Shownkeen R., Sims M., Smaldon N., Smith A., Smith M.,
RA Sonnhammer E., Staden R., Sulston J., Thierry-Mieg J., Thomas K.,
RA Vaudin M., Vaughan K., Waterston R., Watson A., Weinstock L.,
RA Wilkinson-Sproat J., Wohldman P.;
RT "2.2 Mb of contiguous nucleotide sequence from chromosome III of C.
RT elegans.";
RL Nature 368:32-38(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=b {ECO:0000312|WormBase:ZK1236.7b};
CC IsoId=P34623-1; Sequence=Displayed;
CC Name=a {ECO:0000312|WormBase:ZK1236.7a};
CC IsoId=P34623-2; Sequence=VSP_057668;
CC -!- SIMILARITY: Belongs to the DDRGK1 family. {ECO:0000305}.
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DR EMBL; FO080723; CCD66167.1; -; Genomic_DNA.
DR EMBL; FO080723; CCF23348.1; -; Genomic_DNA.
DR PIR; S44785; S44785.
DR PIR; S44893; S44893.
DR RefSeq; NP_001254959.1; NM_001268030.1. [P34623-2]
DR RefSeq; NP_001254960.1; NM_001268031.1.
DR AlphaFoldDB; P34623; -.
DR SMR; P34623; -.
DR BioGRID; 41398; 4.
DR STRING; 6239.ZK1236.7a; -.
DR EPD; P34623; -.
DR PaxDb; P34623; -.
DR PeptideAtlas; P34623; -.
DR PRIDE; P34623; -.
DR EnsemblMetazoa; ZK1236.7a.1; ZK1236.7a.1; WBGene00022865. [P34623-2]
DR EnsemblMetazoa; ZK1236.7b.1; ZK1236.7b.1; WBGene00022865. [P34623-1]
DR GeneID; 176194; -.
DR KEGG; cel:CELE_ZK1236.7; -.
DR CTD; 176194; -.
DR WormBase; ZK1236.7a; CE29628; WBGene00022865; ufbp-1. [P34623-2]
DR WormBase; ZK1236.7b; CE46881; WBGene00022865; ufbp-1. [P34623-1]
DR eggNOG; KOG3054; Eukaryota.
DR GeneTree; ENSGT00390000017193; -.
DR HOGENOM; CLU_059562_1_0_1; -.
DR InParanoid; P34623; -.
DR OMA; DGFVNHM; -.
DR OrthoDB; 1455985at2759; -.
DR PhylomeDB; P34623; -.
DR PRO; PR:P34623; -.
DR Proteomes; UP000001940; Chromosome III.
DR Bgee; WBGene00022865; Expressed in adult organism and 4 other tissues.
DR GO; GO:0005634; C:nucleus; HDA:WormBase.
DR Gene3D; 1.10.10.10; -; 1.
DR InterPro; IPR019153; DDRGK_dom-contain.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR Pfam; PF09756; DDRGK; 1.
DR SMART; SM01128; DDRGK; 1.
DR SUPFAM; SSF46785; SSF46785; 1.
PE 3: Inferred from homology;
KW Alternative splicing; Reference proteome; Signal.
FT SIGNAL 1..26
FT /evidence="ECO:0000255"
FT CHAIN 27..302
FT /note="DDRGK domain-containing protein 1"
FT /evidence="ECO:0000305"
FT /id="PRO_0000065566"
FT REGION 101..178
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 1
FT /note="M -> MDNNQEKSTDSPYSFGGTKDDGM (in isoform a)"
FT /evidence="ECO:0000305"
FT /id="VSP_057668"
SQ SEQUENCE 302 AA; 35071 MW; 7A1A3CC1E081B2C5 CRC64;
MDPLLLGSVG VLVLAVTLII WRLLKLQWDE KAARQRTDML LAMNEGAGGS DERRGANVAG
GMRRNARRRV NRDEQEDGFV NHMMNDGEDV EDLDGGAEQF EYDEDGKKIG KRKAAKLQAK
EEKRQMREYE VREREERKRR EEEREKKRDE ERAKEEADEK AEEERLRKER EEKERKEHEE
YLAMKASFAI EEEGTDAIEG EEAENLIRDF VDYVKTNKVV NIDELSSHFG LKSEDAVNRL
QHFIEEGLVQ GVMDDRGKFI YISDEEFAAV AKFINQRGRV SIHEIAEQSN RLIRLETPSA
AE