ID   DDRGK_CULQU             Reviewed;         287 AA.
AC   B0WIW5;
DT   02-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 1.
DT   03-AUG-2022, entry version 59.
DE   RecName: Full=DDRGK domain-containing protein 1;
DE   Flags: Precursor;
GN   ORFNames=CPIJ007479;
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB;
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.D.,
RA   Hannick L.I., Megy K., O'Leary S.B., Pearson M., Haas B.J., Mauceli E.,
RA   Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA   Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA   Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA   Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA   Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA   Fraser-Liggett C.M., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Substrate adapter for ufmylation, the covalent attachment of
CC       the ubiquitin-like modifier UFM1 to substrate proteins.
CC       {ECO:0000250|UniProtKB:Q96HY6}.
CC   -!- SIMILARITY: Belongs to the DDRGK1 family. {ECO:0000305}.
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DR   EMBL; DS231953; EDS28791.1; -; Genomic_DNA.
DR   RefSeq; XP_001848649.1; XM_001848597.1.
DR   AlphaFoldDB; B0WIW5; -.
DR   SMR; B0WIW5; -.
DR   STRING; 7176.CPIJ007479-PA; -.
DR   PRIDE; B0WIW5; -.
DR   GeneID; 6038960; -.
DR   KEGG; cqu:CpipJ_CPIJ007479; -.
DR   VEuPathDB; VectorBase:CPIJ007479; -.
DR   VEuPathDB; VectorBase:CQUJHB011994; -.
DR   eggNOG; KOG3054; Eukaryota.
DR   HOGENOM; CLU_059562_1_0_1; -.
DR   InParanoid; B0WIW5; -.
DR   OMA; QEFIQYI; -.
DR   OrthoDB; 1431890at2759; -.
DR   PhylomeDB; B0WIW5; -.
DR   Proteomes; UP000002320; Partially assembled WGS sequence.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR019153; DDRGK_dom-contain.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF09756; DDRGK; 1.
DR   SMART; SM01128; DDRGK; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Signal; Ubl conjugation pathway.
FT   SIGNAL          1..28
FT                   /evidence="ECO:0000255"
FT   CHAIN           29..287
FT                   /note="DDRGK domain-containing protein 1"
FT                   /id="PRO_0000391856"
FT   REGION          28..102
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          135..164
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        74..102
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   287 AA;  32733 MW;  AFC424B2806E8077 CRC64;
     MDLILLLGIA VALLVILVTL FFFTKGKGSQ ESGKYNHPRV ENEAQAAPRR AQVVRNQRNR
     ARVAAAPAEE QHHAAADGGS DEDEIPHADF NGEKMGAKKR AKLEAKAEKK ALREQELKIR
     EDQKKKDALL EEQRKVEAEK EAEEERKREE AEKKAREEKA RQEHEEYLRM KEAFSVEEEG
     FDQEQEDDKQ NMLQEFINFV KSNKVVVLED LAVQFKLKTQ AAIDRIVELQ KDGRLSGVID
     DRGKFIYISE EELNAVAKFI KQRGRVSITE LAENSNNLIN LVPVSAE