ID   DDRGK_DICDI             Reviewed;         335 AA.
AC   Q55CM7;
DT   02-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=DDRGK domain-containing protein 1;
DE   Flags: Precursor;
GN   ORFNames=DDB_G0269994;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Substrate adapter for ufmylation, the covalent attachment of
CC       the ubiquitin-like modifier UFM1 to substrate proteins.
CC       {ECO:0000250|UniProtKB:Q96HY6}.
CC   -!- SIMILARITY: Belongs to the DDRGK1 family. {ECO:0000305}.
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DR   EMBL; AAFI02000005; EAL72347.1; -; Genomic_DNA.
DR   RefSeq; XP_646454.1; XM_641362.1.
DR   AlphaFoldDB; Q55CM7; -.
DR   SMR; Q55CM7; -.
DR   STRING; 44689.DDB0190724; -.
DR   PaxDb; Q55CM7; -.
DR   EnsemblProtists; EAL72347; EAL72347; DDB_G0269994.
DR   GeneID; 8617414; -.
DR   KEGG; ddi:DDB_G0269994; -.
DR   dictyBase; DDB_G0269994; -.
DR   eggNOG; KOG3054; Eukaryota.
DR   HOGENOM; CLU_059562_1_0_1; -.
DR   InParanoid; Q55CM7; -.
DR   OMA; QEFIQYI; -.
DR   PRO; PR:Q55CM7; -.
DR   Proteomes; UP000002195; Chromosome 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR019153; DDRGK_dom-contain.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF09756; DDRGK; 1.
DR   SMART; SM01128; DDRGK; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Signal; Ubl conjugation pathway.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..335
FT                   /note="DDRGK domain-containing protein 1"
FT                   /id="PRO_0000391869"
FT   REGION          37..124
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        37..61
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   335 AA;  38954 MW;  0B3BD1561ED6D331 CRC64;
     MGDTYSLVLV AGYLSIFLFI GAIGYFYLSK PRIPSSNVNE QQQQQQQQQQ QQQQPQINIE
     DEPQQRGGIG RMNLRNRRQP IINQRDEDTE SSGSDSDNST NSDNYDDDNG QEGEGEDIGV
     VAPGIVSNRS GKKIGKKKLE KLKLKDEKRK AREYQEYLRE EKKKTDLEKE EALKEKRLEE
     KENEKLRKEE EERIRIEKER KEDEEYNLLK SQISLQESGI TKNEDYDKSL LQLFIKYLKE
     HKICLLEDIA IEFNIKTNEV IDRIKTLDKQ GLISGVIDDR GKFIYITKEE MEAVAKFVNK
     KGRVNIEQIA LESNRLIDFS KKVVDNNDQD PVDTN