ID   DDRGK_DROAN             Reviewed;         304 AA.
AC   B3MTS7;
DT   02-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT   02-SEP-2008, sequence version 1.
DT   03-AUG-2022, entry version 50.
DE   RecName: Full=DDRGK domain-containing protein 1;
DE   Flags: Precursor;
GN   ORFNames=GF23066;
OS   Drosophila ananassae (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7217;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tucson 14024-0371.13;
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- FUNCTION: Substrate adapter for ufmylation, the covalent attachment of
CC       the ubiquitin-like modifier UFM1 to substrate proteins.
CC       {ECO:0000250|UniProtKB:Q96HY6}.
CC   -!- SIMILARITY: Belongs to the DDRGK1 family. {ECO:0000305}.
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DR   EMBL; CH902623; EDV30208.1; -; Genomic_DNA.
DR   RefSeq; XP_001964412.1; XM_001964376.2.
DR   AlphaFoldDB; B3MTS7; -.
DR   SMR; B3MTS7; -.
DR   STRING; 7217.FBpp0126258; -.
DR   EnsemblMetazoa; FBtr0127766; FBpp0126258; FBgn0100060.
DR   GeneID; 6505712; -.
DR   KEGG; dan:6505712; -.
DR   eggNOG; KOG3054; Eukaryota.
DR   HOGENOM; CLU_059562_1_0_1; -.
DR   InParanoid; B3MTS7; -.
DR   OMA; QEFIQYI; -.
DR   OrthoDB; 1446840at2759; -.
DR   PhylomeDB; B3MTS7; -.
DR   Proteomes; UP000007801; Unassembled WGS sequence.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR019153; DDRGK_dom-contain.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF09756; DDRGK; 1.
DR   SMART; SM01128; DDRGK; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Signal; Ubl conjugation pathway.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..304
FT                   /note="DDRGK domain-containing protein 1"
FT                   /id="PRO_0000391857"
FT   REGION          31..174
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        107..174
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   304 AA;  33759 MW;  E21CCF60832D59DE CRC64;
     MDLIILVGIA IALLVVIISL YLLQKKNSTT EAKPAAAAPQ RGVPQRAQEG VPRRAQIARN
     QRNRLRQNAP VAAAAPQAEA PAGSDNDDDA QADGEGARLP QGAVLDEKMG AKKRAKMEAK
     EAKRVQREQE LYDREQRKAK EAKEDAERKQ QEEIEAEAER KKAEAERLAK EERERKEHEE
     YLKMKAAFSV EEEGFEEGDA DEQDNLLADF IQYIKDNKVV VLEDLAVAFK LKTQQAIDRI
     QELQADGTIT GVIDDRGKFI YVSEEELVAV AKFIKQRGRV SIADLAESSN NLINLTPVSA
     EGSS