ID   DDRGK_DROER             Reviewed;         312 AA.
AC   B3P045;
DT   02-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT   02-SEP-2008, sequence version 1.
DT   25-MAY-2022, entry version 44.
DE   RecName: Full=DDRGK domain-containing protein 1;
DE   Flags: Precursor;
GN   ORFNames=GG24454;
OS   Drosophila erecta (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7220;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tucson 14021-0224.01;
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- FUNCTION: Substrate adapter for ufmylation, the covalent attachment of
CC       the ubiquitin-like modifier UFM1 to substrate proteins.
CC       {ECO:0000250|UniProtKB:Q96HY6}.
CC   -!- SIMILARITY: Belongs to the DDRGK1 family. {ECO:0000305}.
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DR   EMBL; CH954181; EDV48281.1; -; Genomic_DNA.
DR   RefSeq; XP_001979323.1; XM_001979287.2.
DR   AlphaFoldDB; B3P045; -.
DR   SMR; B3P045; -.
DR   STRING; 7220.FBpp0143000; -.
DR   EnsemblMetazoa; FBtr0144508; FBpp0143000; FBgn0116586.
DR   GeneID; 6553540; -.
DR   KEGG; der:6553540; -.
DR   eggNOG; KOG3054; Eukaryota.
DR   HOGENOM; CLU_059562_1_0_1; -.
DR   OMA; HIAMESK; -.
DR   OrthoDB; 1446840at2759; -.
DR   PhylomeDB; B3P045; -.
DR   Proteomes; UP000008711; Unassembled WGS sequence.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR019153; DDRGK_dom-contain.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF09756; DDRGK; 1.
DR   SMART; SM01128; DDRGK; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
PE   3: Inferred from homology;
KW   Signal; Ubl conjugation pathway.
FT   SIGNAL          1..28
FT                   /evidence="ECO:0000255"
FT   CHAIN           29..312
FT                   /note="DDRGK domain-containing protein 1"
FT                   /id="PRO_0000391858"
FT   REGION          30..163
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        86..100
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        112..163
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   312 AA;  34732 MW;  4D95A744457B3098 CRC64;
     MELIILVGIA IALLVVIITL YLLQKKNAAP ETKPAAAPQR GVPQRAQEGV PRRAQIARNQ
     RNRLRQNAPA APAGQVAPAA GAPAARGDSD HEDEGQVDAD DARVPQGAVL DEKMGAKKRA
     KMEAKEQKRL QREQELHDRE QRKVKEAKEE AERKQQEDLE AEVERKRVEA ERLAKEERER
     KEHEEYLKMK AAFSVEEEGF EEGDADEQDS LLAGFIQYIR DNKVVVLEDL AVAFKLKTQQ
     VIDRIQELQA DGTLTGVIDD RGKFIYVSEE ELSAVAKFIK QRGRVSITEL AESSNNLINL
     TPISAGGEEA SS