ID   DDRGK_DROMO             Reviewed;         310 AA.
AC   B4KB40;
DT   02-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   03-AUG-2022, entry version 51.
DE   RecName: Full=DDRGK domain-containing protein 1;
DE   Flags: Precursor;
GN   ORFNames=GI22611;
OS   Drosophila mojavensis (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila.
OX   NCBI_TaxID=7230;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tucson 15081-1352.22;
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- FUNCTION: Substrate adapter for ufmylation, the covalent attachment of
CC       the ubiquitin-like modifier UFM1 to substrate proteins.
CC       {ECO:0000250|UniProtKB:Q96HY6}.
CC   -!- SIMILARITY: Belongs to the DDRGK1 family. {ECO:0000305}.
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DR   EMBL; CH933806; EDW15744.1; -; Genomic_DNA.
DR   RefSeq; XP_002000283.1; XM_002000247.2.
DR   AlphaFoldDB; B4KB40; -.
DR   SMR; B4KB40; -.
DR   STRING; 7230.FBpp0171828; -.
DR   EnsemblMetazoa; FBtr0173336; FBpp0171828; FBgn0145339.
DR   GeneID; 6574225; -.
DR   KEGG; dmo:Dmoj_GI22611; -.
DR   eggNOG; KOG3054; Eukaryota.
DR   HOGENOM; CLU_059562_1_0_1; -.
DR   InParanoid; B4KB40; -.
DR   OMA; QEFIQYI; -.
DR   OrthoDB; 1446840at2759; -.
DR   PhylomeDB; B4KB40; -.
DR   Proteomes; UP000009192; Unassembled WGS sequence.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR019153; DDRGK_dom-contain.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF09756; DDRGK; 1.
DR   SMART; SM01128; DDRGK; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Signal; Ubl conjugation pathway.
FT   SIGNAL          1..28
FT                   /evidence="ECO:0000255"
FT   CHAIN           29..310
FT                   /note="DDRGK domain-containing protein 1"
FT                   /id="PRO_0000391861"
FT   REGION          31..52
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          91..157
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        111..157
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   310 AA;  34443 MW;  7E9B7D00D66B7DB3 CRC64;
     MDLILLVGIA IALLVILITL YFLQNKNSKT ETKAAAQPQR GVPQRAQEGV PRRAQIARNQ
     RNRLRANQNA PAAAAAAAAP AAAAIDTDND EAAAAGDENG PRVPQGAVLD EKMGAKKRAK
     MEAKEQKRLQ REQELHDREQ RKVKEAKEDA ERKQQEELEA EVERKRVEAE RLAKEEREHK
     EHEEYLKMKA AFSIEEEGFE EGDADEKESL LADFIQYIKD NKVVLLEDLA TAFKLKTQQA
     IERIQELQAN GTITGVIDDR GKFIYVSEAE LAAVAKFIKQ RGRVSIADLA ESSNKLINLT
     PVATGEGSVQ