ID   DDRGK_DROSI             Reviewed;         293 AA.
AC   B4R133;
DT   02-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   03-AUG-2022, entry version 48.
DE   RecName: Full=DDRGK domain-containing protein 1;
DE   Flags: Precursor;
GN   ORFNames=GD19406;
OS   Drosophila simulans (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7240;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- FUNCTION: Substrate adapter for ufmylation, the covalent attachment of
CC       the ubiquitin-like modifier UFM1 to substrate proteins.
CC       {ECO:0000250|UniProtKB:Q96HY6}.
CC   -!- SIMILARITY: Belongs to the DDRGK1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CM000364; EDX12120.1; -; Genomic_DNA.
DR   AlphaFoldDB; B4R133; -.
DR   SMR; B4R133; -.
DR   STRING; 7240.B4R133; -.
DR   PRIDE; B4R133; -.
DR   HOGENOM; CLU_059562_1_0_1; -.
DR   OMA; HIAMESK; -.
DR   PhylomeDB; B4R133; -.
DR   Proteomes; UP000000304; Chromosome 3r.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR019153; DDRGK_dom-contain.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF09756; DDRGK; 1.
DR   SMART; SM01128; DDRGK; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Signal; Ubl conjugation pathway.
FT   SIGNAL          1..28
FT                   /evidence="ECO:0000255"
FT   CHAIN           29..293
FT                   /note="DDRGK domain-containing protein 1"
FT                   /id="PRO_0000391864"
FT   REGION          30..158
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        109..158
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   293 AA;  32660 MW;  ABBB6C3A04CAAEBF CRC64;
     MELIILVGIA VALLVVIVTL YLLQKKNAAP ETKAAAAPQR GVPQRAQEGV PRRAQIARNQ
     RNRLRQNVPA APVAAAAGAP PAAGDSDHED EGQVDGDEAR VPQGAVLDEK MGAKKRAKME
     AKEQKRLQRE QELHDREQRK VKEAKEEAER KQQEDLEAEV ERKRVDAERL AKEERERKEH
     EEYLKMKAAF SVEEEGFEEG DADDQDNLLA DFIQYIRDNK VVVLEDLAVA FKLKTQQVID
     RIQELQADGT ITGVIDDRGK FIYVSEEELL AVASSLNNAD ASPSPSWPRA ATT