DDT4L_BOVIN
ID DDT4L_BOVIN Reviewed; 193 AA.
AC A2VDT9;
DT 23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 20-MAR-2007, sequence version 1.
DT 03-AUG-2022, entry version 59.
DE RecName: Full=DNA damage-inducible transcript 4-like protein;
GN Name=DDIT4L;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Fetal muscle;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Inhibits cell growth by regulating the TOR signaling pathway
CC upstream of the TSC1-TSC2 complex and downstream of AKT1.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the DDIT4 family. {ECO:0000305}.
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DR EMBL; BC133398; AAI33399.1; -; mRNA.
DR RefSeq; NP_001074988.1; NM_001081519.1.
DR AlphaFoldDB; A2VDT9; -.
DR SMR; A2VDT9; -.
DR STRING; 9913.ENSBTAP00000014026; -.
DR PaxDb; A2VDT9; -.
DR PRIDE; A2VDT9; -.
DR Ensembl; ENSBTAT00000014026; ENSBTAP00000014026; ENSBTAG00000010610.
DR GeneID; 510906; -.
DR KEGG; bta:510906; -.
DR CTD; 115265; -.
DR VEuPathDB; HostDB:ENSBTAG00000010610; -.
DR VGNC; VGNC:27949; DDIT4L.
DR eggNOG; ENOG502R3EE; Eukaryota.
DR GeneTree; ENSGT00530000063652; -.
DR HOGENOM; CLU_086145_0_0_1; -.
DR InParanoid; A2VDT9; -.
DR OMA; FAPTFRH; -.
DR OrthoDB; 1588396at2759; -.
DR TreeFam; TF105007; -.
DR Proteomes; UP000009136; Chromosome 6.
DR Bgee; ENSBTAG00000010610; Expressed in biceps femoris and 95 other tissues.
DR GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR GO; GO:0009968; P:negative regulation of signal transduction; IEA:InterPro.
DR Gene3D; 3.90.470.40; -; 1.
DR InterPro; IPR012918; RTP801-like.
DR InterPro; IPR038281; RTP801-like_C_sf.
DR PANTHER; PTHR12478; PTHR12478; 1.
DR Pfam; PF07809; RTP801_C; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Reference proteome.
FT CHAIN 1..193
FT /note="DNA damage-inducible transcript 4-like protein"
FT /id="PRO_0000307203"
SQ SEQUENCE 193 AA; 21803 MW; C40F7473C58B7159 CRC64;
MVATGSLSSK NPASISELLD HGFYPGSLLN DFDYWDYVVP EPNLNEVVFE ETTCQSLVKM
LENCLSKSKH TKLGCSRVLV PEKLTQRIAQ DVLRLSSTEP CGLRGCVMHV NLEIENVCKK
LDRIVCDSSV VPTFELTLVF KQENCSWTSF RDFFFSRGRF SSGLRRTLIL SSGFRLVKKK
LYSLIGTTVI EEC