ID   DDT4L_PONAB             Reviewed;         193 AA.
AC   Q5R8K0;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 44.
DE   RecName: Full=DNA damage-inducible transcript 4-like protein;
GN   Name=DDIT4L;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Inhibits cell growth by regulating the TOR signaling pathway
CC       upstream of the TSC1-TSC2 complex and downstream of AKT1.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the DDIT4 family. {ECO:0000305}.
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DR   EMBL; CR859752; CAH91910.1; -; mRNA.
DR   RefSeq; NP_001126106.1; NM_001132634.1.
DR   AlphaFoldDB; Q5R8K0; -.
DR   SMR; Q5R8K0; -.
DR   STRING; 9601.ENSPPYP00000016703; -.
DR   GeneID; 100173061; -.
DR   KEGG; pon:100173061; -.
DR   CTD; 115265; -.
DR   eggNOG; ENOG502R3EE; Eukaryota.
DR   InParanoid; Q5R8K0; -.
DR   OrthoDB; 1588396at2759; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0009968; P:negative regulation of signal transduction; IEA:InterPro.
DR   Gene3D; 3.90.470.40; -; 1.
DR   InterPro; IPR012918; RTP801-like.
DR   InterPro; IPR038281; RTP801-like_C_sf.
DR   PANTHER; PTHR12478; PTHR12478; 1.
DR   Pfam; PF07809; RTP801_C; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..193
FT                   /note="DNA damage-inducible transcript 4-like protein"
FT                   /id="PRO_0000307206"
SQ   SEQUENCE   193 AA;  21685 MW;  41BD2C58084D235D CRC64;
     MVATGSLSGK NPASISELLD CGYRPESLLS DFDYWDYVVP EPNLNEVIFE ESTCQNLVKM
     LENCLSKSKQ TKLGCSKVLV PEKLTQRIAQ DVLRLSSTEP CGLRGCVMHV NLEIENVCKK
     LDRIVCDSSV VPTFELTLVF KQENCSWSSF RDFFFSRGRF SSGFRRTLIL SSGFRLVKKK
     LYSLIGATVI EGS