ACYP2_BOVIN
ID ACYP2_BOVIN Reviewed; 99 AA.
AC P07033;
DT 01-APR-1988, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 03-AUG-2022, entry version 130.
DE RecName: Full=Acylphosphatase-2;
DE EC=3.6.1.7;
DE AltName: Full=Acylphosphatase, muscle type isozyme;
DE AltName: Full=Acylphosphate phosphohydrolase 2;
GN Name=ACYP2; Synonyms=ACYP;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP PROTEIN SEQUENCE OF 2-99, AND ACETYLATION AT SER-2.
RC TISSUE=Muscle;
RX PubMed=3011706;
RA Camici G., Manao G., Modesti A., Stefani M., Berti A., Cappugi G.,
RA Ramponi G.;
RT "The complete amino acid sequence of bovine skeletal muscle
RT acylphosphatase.";
RL Ital. J. Biochem. 35:1-15(1986).
CC -!- FUNCTION: Its physiological role is not yet clear.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=an acyl phosphate + H2O = a carboxylate + H(+) + phosphate;
CC Xref=Rhea:RHEA:14965, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:29067, ChEBI:CHEBI:43474, ChEBI:CHEBI:59918; EC=3.6.1.7;
CC -!- SIMILARITY: Belongs to the acylphosphatase family. {ECO:0000305}.
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DR PIR; A29578; QPBO.
DR RefSeq; NP_001106701.1; NM_001113230.1.
DR AlphaFoldDB; P07033; -.
DR SMR; P07033; -.
DR STRING; 9913.ENSBTAP00000008994; -.
DR iPTMnet; P07033; -.
DR PaxDb; P07033; -.
DR Ensembl; ENSBTAT00000008994; ENSBTAP00000008994; ENSBTAG00000006852.
DR GeneID; 767889; -.
DR KEGG; bta:767889; -.
DR CTD; 98; -.
DR VEuPathDB; HostDB:ENSBTAG00000006852; -.
DR VGNC; VGNC:25599; ACYP2.
DR eggNOG; KOG3360; Eukaryota.
DR GeneTree; ENSGT00390000011103; -.
DR HOGENOM; CLU_141932_0_1_1; -.
DR InParanoid; P07033; -.
DR OMA; HAIMAEN; -.
DR OrthoDB; 1502266at2759; -.
DR TreeFam; TF300288; -.
DR Proteomes; UP000009136; Chromosome 11.
DR Bgee; ENSBTAG00000006852; Expressed in semimembranosus muscle and 100 other tissues.
DR GO; GO:0003998; F:acylphosphatase activity; IBA:GO_Central.
DR InterPro; IPR020456; Acylphosphatase.
DR InterPro; IPR001792; Acylphosphatase-like_dom.
DR InterPro; IPR036046; Acylphosphatase-like_dom_sf.
DR InterPro; IPR017968; Acylphosphatase_CS.
DR PANTHER; PTHR10029; PTHR10029; 1.
DR Pfam; PF00708; Acylphosphatase; 1.
DR PRINTS; PR00112; ACYLPHPHTASE.
DR SUPFAM; SSF54975; SSF54975; 1.
DR PROSITE; PS00150; ACYLPHOSPHATASE_1; 1.
DR PROSITE; PS00151; ACYLPHOSPHATASE_2; 1.
DR PROSITE; PS51160; ACYLPHOSPHATASE_3; 1.
PE 1: Evidence at protein level;
KW Acetylation; Direct protein sequencing; Hydrolase; Phosphoprotein;
KW Reference proteome.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000250|UniProtKB:P14621"
FT CHAIN 2..99
FT /note="Acylphosphatase-2"
FT /id="PRO_0000158539"
FT DOMAIN 9..99
FT /note="Acylphosphatase-like"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00520"
FT ACT_SITE 24
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00520"
FT ACT_SITE 42
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00520"
FT MOD_RES 2
FT /note="N-acetylserine"
FT /evidence="ECO:0000269|PubMed:3011706"
FT MOD_RES 93
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:P35745"
SQ SEQUENCE 99 AA; 11178 MW; DEA946D6644A6796 CRC64;
MSTGRPLKSV DYEVFGRVQG VCFRMYTEDE ARKIGVVGWV KNTSKGTVTG QVQGPEEKVN
SMKSWLSKVG SPSSRIDRTN FSNEKTISKL EYSSFNIRY
