DEAL4_ARATH
ID DEAL4_ARATH Reviewed; 204 AA.
AC O23040;
DT 23-FEB-2022, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 112.
DE RecName: Full=Protein DESIGUAL 4 {ECO:0000303|PubMed:29139551};
DE Flags: Precursor;
GN Name=DEAL4 {ECO:0000303|PubMed:29139551};
GN OrderedLocusNames=At1g05291 {ECO:0000312|EMBL:AEE27819.1};
GN ORFNames=YUP8H12.9 {ECO:0000312|EMBL:AAB71448.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP TISSUE SPECIFICITY, GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Columbia;
RX PubMed=29139551; DOI=10.1111/nph.14898;
RA Wilson-Sanchez D., Martinez-Lopez S., Navarro-Cartagena S., Jover-Gil S.,
RA Micol J.L.;
RT "Members of the DEAL subfamily of the DUF1218 gene family are required for
RT bilateral symmetry but not for dorsoventrality in Arabidopsis leaves.";
RL New Phytol. 217:1307-1321(2018).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000250|UniProtKB:Q9ZV57}; Multi-pass membrane protein
CC {ECO:0000255}.
CC -!- TISSUE SPECIFICITY: Only expressed in inflorescences.
CC {ECO:0000269|PubMed:29139551}.
CC -!- SIMILARITY: Belongs to the DESIGUAL family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC000098; AAB71448.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE27819.1; -; Genomic_DNA.
DR PIR; F86187; F86187.
DR RefSeq; NP_001117232.1; NM_001123760.1.
DR AlphaFoldDB; O23040; -.
DR PaxDb; O23040; -.
DR EnsemblPlants; AT1G05291.1; AT1G05291.1; AT1G05291.
DR GeneID; 6240483; -.
DR Gramene; AT1G05291.1; AT1G05291.1; AT1G05291.
DR KEGG; ath:AT1G05291; -.
DR Araport; AT1G05291; -.
DR TAIR; locus:4515102499; AT1G05291.
DR HOGENOM; CLU_103513_0_0_1; -.
DR InParanoid; O23040; -.
DR OMA; NVIGCSI; -.
DR OrthoDB; 1412654at2759; -.
DR PhylomeDB; O23040; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; O23040; baseline and differential.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR009606; DEAL/Modifying_wall_lignin1/2.
DR Pfam; PF06749; DUF1218; 1.
PE 2: Evidence at transcript level;
KW Developmental protein; Endoplasmic reticulum; Glycoprotein; Membrane;
KW Reference proteome; Signal; Transmembrane; Transmembrane helix.
FT SIGNAL 1..?
FT /evidence="ECO:0000255"
FT CHAIN ?..204
FT /note="Protein DESIGUAL 4"
FT /id="PRO_0000454968"
FT TRANSMEM 13..33
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 60..80
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 107..127
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 143..163
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 177..204
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 179
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
SQ SEQUENCE 204 AA; 22055 MW; 91502ADC18380B27 CRC64;
MEEGKGTEKK GCIITVIIVC IVLTVGLDIV AGFVGLQAQA AQQYVKHDKL ECKAPSKTAF
VLGIIAVSCL ATAHVSANVI GCSISNLFQA LGALPKNKIT TYFNMACLFL IWVVGIFGAL
ILANGIWSNT ESRIRCRFTN NHVFSIGGKV CFLHAIVSGI YYISSIVARA RHFHRTKPNK
TKPSELKPIP TEPNEAEPNS TPNP
