DEC1_DROER
ID DEC1_DROER Reviewed; 557 AA.
AC Q23933; Q23934;
DT 16-MAY-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 2.
DT 25-MAY-2022, entry version 73.
DE RecName: Full=Defective chorion-1 protein;
DE Flags: Precursor; Fragments;
GN Name=dec-1;
OS Drosophila erecta (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7220;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=1774787; DOI=10.1007/bf02102863;
RA Andersson S., Lambertsson A.;
RT "Evolution of the dec-1 eggshell locus in Drosophila. I. Restriction site
RT mapping and limited sequence comparison in the melanogaster species
RT subgroup.";
RL J. Mol. Evol. 33:321-331(1991).
CC -!- FUNCTION: Required for proper assembly of the eggshell.
CC {ECO:0000250|UniProtKB:P18169}.
CC -!- SUBCELLULAR LOCATION: Secreted.
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DR EMBL; X76232; CAA53817.1; -; Genomic_DNA.
DR EMBL; X76233; CAA53818.1; -; Genomic_DNA.
DR AlphaFoldDB; Q23933; -.
DR GO; GO:0042600; C:egg chorion; ISS:UniProtKB.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005213; F:structural constituent of egg chorion; ISS:UniProtKB.
DR GO; GO:0007306; P:eggshell chorion assembly; ISS:UniProtKB.
DR InterPro; IPR006719; DEC-1_N.
DR InterPro; IPR006718; DEC-1_REPEAT.
DR Pfam; PF04624; Dec-1; 1.
DR Pfam; PF04625; DEC-1_N; 3.
PE 3: Inferred from homology;
KW Repeat; Secreted; Signal.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT CHAIN 22..557
FT /note="Defective chorion-1 protein"
FT /id="PRO_0000021102"
FT REPEAT 458..483
FT /note="1"
FT /evidence="ECO:0000305"
FT REPEAT 484..509
FT /note="2"
FT /evidence="ECO:0000305"
FT REPEAT 510..535
FT /note="3"
FT /evidence="ECO:0000305"
FT REGION 23..60
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 186..210
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 458..535
FT /note="3 X 26 AA tandem repeats of Q-[SG]-P-M-[MT]-M-[EQ]-
FT Q-R-Q-[WS]-[SA]-E-D-Q-A-K-[IM]-Q-Q-[NS]-P-[QM]-[QMV]-[IM]-
FT Q"
FT REGION 485..534
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..45
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 186..209
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_CONS 389..390
FT /evidence="ECO:0000305"
FT NON_TER 557
FT /evidence="ECO:0000305"
SQ SEQUENCE 557 AA; 61573 MW; 86004009AE1F53FE CRC64;
MRLYSHLPLL ALLVVQAVGQ SQVTSEDPAR DAGSTSNSTA ATRPRIPSQE EILGQMPPIP
PIRTGSPQMD VFYMMFPALG SLLRWGSLFP AQSILGAMPD NLQPEAAASR VVLVLADDAT
AKARVVRQNP PLNPLGQLMN WPALPQDFQL PSMDLGPQVG SFLAQLPPMP AIPSILGAAA
PVPAPAPAPA ATPLAPAPAA DPPAAPVPDA AQPAILGQAA LQNAFTFLNP SNFDASGLLG
QSAPTFAPPN FDFVAQMQRQ FFPGMTPAQQ PAPAGTDALA SDISEVRVRP EAPYSQEAQM
KIKSALEMEQ ERQQQAQVKD QEQVPLLWFH MPTTQAQVKD QEQVPLLWFH MPTTQNQDAT
AEKTLEDLRV EAKLRAFERQ VISELRMLQK EAQRRAGNSG MNSQKANALK RQAKSQEQAL
SKEDIVQIMA YAYRMANEQM ESEKGKQDKV YAAYRTEQSP MTMEQRQWSE DQAKIQQNPQ
QIQQGPMMMQ QRQSAEDQAK MQQSPMMMQQ SPMMMQQRQS AEDQAKMQQS PMVMQQSPMM
MQQSPMMMQQ RQWTEDP