ID   DEC1_DROER              Reviewed;         557 AA.
AC   Q23933; Q23934;
DT   16-MAY-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 2.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Defective chorion-1 protein;
DE   Flags: Precursor; Fragments;
GN   Name=dec-1;
OS   Drosophila erecta (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7220;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1774787; DOI=10.1007/bf02102863;
RA   Andersson S., Lambertsson A.;
RT   "Evolution of the dec-1 eggshell locus in Drosophila. I. Restriction site
RT   mapping and limited sequence comparison in the melanogaster species
RT   subgroup.";
RL   J. Mol. Evol. 33:321-331(1991).
CC   -!- FUNCTION: Required for proper assembly of the eggshell.
CC       {ECO:0000250|UniProtKB:P18169}.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X76232; CAA53817.1; -; Genomic_DNA.
DR   EMBL; X76233; CAA53818.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q23933; -.
DR   GO; GO:0042600; C:egg chorion; ISS:UniProtKB.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005213; F:structural constituent of egg chorion; ISS:UniProtKB.
DR   GO; GO:0007306; P:eggshell chorion assembly; ISS:UniProtKB.
DR   InterPro; IPR006719; DEC-1_N.
DR   InterPro; IPR006718; DEC-1_REPEAT.
DR   Pfam; PF04624; Dec-1; 1.
DR   Pfam; PF04625; DEC-1_N; 3.
PE   3: Inferred from homology;
KW   Repeat; Secreted; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..557
FT                   /note="Defective chorion-1 protein"
FT                   /id="PRO_0000021102"
FT   REPEAT          458..483
FT                   /note="1"
FT                   /evidence="ECO:0000305"
FT   REPEAT          484..509
FT                   /note="2"
FT                   /evidence="ECO:0000305"
FT   REPEAT          510..535
FT                   /note="3"
FT                   /evidence="ECO:0000305"
FT   REGION          23..60
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          186..210
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          458..535
FT                   /note="3 X 26 AA tandem repeats of Q-[SG]-P-M-[MT]-M-[EQ]-
FT                   Q-R-Q-[WS]-[SA]-E-D-Q-A-K-[IM]-Q-Q-[NS]-P-[QM]-[QMV]-[IM]-
FT                   Q"
FT   REGION          485..534
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        23..45
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        186..209
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_CONS        389..390
FT                   /evidence="ECO:0000305"
FT   NON_TER         557
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   557 AA;  61573 MW;  86004009AE1F53FE CRC64;
     MRLYSHLPLL ALLVVQAVGQ SQVTSEDPAR DAGSTSNSTA ATRPRIPSQE EILGQMPPIP
     PIRTGSPQMD VFYMMFPALG SLLRWGSLFP AQSILGAMPD NLQPEAAASR VVLVLADDAT
     AKARVVRQNP PLNPLGQLMN WPALPQDFQL PSMDLGPQVG SFLAQLPPMP AIPSILGAAA
     PVPAPAPAPA ATPLAPAPAA DPPAAPVPDA AQPAILGQAA LQNAFTFLNP SNFDASGLLG
     QSAPTFAPPN FDFVAQMQRQ FFPGMTPAQQ PAPAGTDALA SDISEVRVRP EAPYSQEAQM
     KIKSALEMEQ ERQQQAQVKD QEQVPLLWFH MPTTQAQVKD QEQVPLLWFH MPTTQNQDAT
     AEKTLEDLRV EAKLRAFERQ VISELRMLQK EAQRRAGNSG MNSQKANALK RQAKSQEQAL
     SKEDIVQIMA YAYRMANEQM ESEKGKQDKV YAAYRTEQSP MTMEQRQWSE DQAKIQQNPQ
     QIQQGPMMMQ QRQSAEDQAK MQQSPMMMQQ SPMMMQQRQS AEDQAKMQQS PMVMQQSPMM
     MQQSPMMMQQ RQWTEDP