ID   DECR_ECO57              Reviewed;         152 AA.
AC   P0ACJ7; P54986; P71209; P77575;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 1.
DT   03-AUG-2022, entry version 107.
DE   RecName: Full=DNA-binding transcriptional activator DecR;
GN   Name=decR; OrderedLocusNames=Z0555, ECs0501;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Plays a role in L-cysteine detoxification. Binds to the
CC       dlsT(yhaO)-yhaM operon promoter in the presence but not absence of L-
CC       cysteine; activates transcription from the dlsT(yhaO)-yhaM operon.
CC       {ECO:0000250|UniProtKB:P0ACJ5}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAB33924.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE005174; AAG54797.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB33924.1; ALT_INIT; Genomic_DNA.
DR   PIR; A85542; A85542.
DR   RefSeq; NP_308528.2; NC_002695.1.
DR   RefSeq; WP_000884589.1; NZ_SWKA01000005.1.
DR   AlphaFoldDB; P0ACJ7; -.
DR   SMR; P0ACJ7; -.
DR   STRING; 155864.EDL933_0521; -.
DR   EnsemblBacteria; AAG54797; AAG54797; Z0555.
DR   EnsemblBacteria; BAB33924; BAB33924; ECs_0501.
DR   GeneID; 67416478; -.
DR   GeneID; 914603; -.
DR   KEGG; ece:Z0555; -.
DR   KEGG; ecs:ECs_0501; -.
DR   PATRIC; fig|386585.9.peg.605; -.
DR   eggNOG; COG1522; Bacteria.
DR   HOGENOM; CLU_091233_0_2_6; -.
DR   OMA; HVSGDYD; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProt.
DR   CDD; cd00090; HTH_ARSR; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR011991; ArsR-like_HTH.
DR   InterPro; IPR000485; AsnC-type_HTH_dom.
DR   InterPro; IPR011008; Dimeric_a/b-barrel.
DR   InterPro; IPR019888; Tscrpt_reg_AsnC-like.
DR   InterPro; IPR019887; Tscrpt_reg_AsnC/Lrp_C.
DR   InterPro; IPR019885; Tscrpt_reg_HTH_AsnC-type_CS.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF01037; AsnC_trans_reg; 1.
DR   PRINTS; PR00033; HTHASNC.
DR   SMART; SM00344; HTH_ASNC; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF54909; SSF54909; 1.
DR   PROSITE; PS00519; HTH_ASNC_1; 1.
DR   PROSITE; PS50956; HTH_ASNC_2; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..152
FT                   /note="DNA-binding transcriptional activator DecR"
FT                   /id="PRO_0000111748"
FT   DOMAIN          2..63
FT                   /note="HTH asnC-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00319"
FT   DNA_BIND        21..40
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00319"
SQ   SEQUENCE   152 AA;  17437 MW;  8409CEDC4CA3D012 CRC64;
     MLDKIDRKLL ALLQQDCTLS LQALAEAVNL TTTPCWKRLK RLEDDGILIG KVALLDPEKI
     GLGLTAFVLI KTQHHSSEWY CRFVTVVTEM PEVLGFWRMA GEYDYLMRVQ VADMKRYDEF
     YKRLVNSVPG LSDVTSSFAM EQIKYTTSLP IE