ID   DECR_ECOL6              Reviewed;         152 AA.
AC   P0ACJ6; P54986; P71209; P77575;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=DNA-binding transcriptional activator DecR;
GN   Name=decR; OrderedLocusNames=c0564;
OS   Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=199310;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CFT073 / ATCC 700928 / UPEC;
RX   PubMed=12471157; DOI=10.1073/pnas.252529799;
RA   Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D.,
RA   Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F.,
RA   Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T.,
RA   Donnenberg M.S., Blattner F.R.;
RT   "Extensive mosaic structure revealed by the complete genome sequence of
RT   uropathogenic Escherichia coli.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002).
CC   -!- FUNCTION: Plays a role in L-cysteine detoxification. Binds to the
CC       dlsT(yhaO)-yhaM operon promoter in the presence but not absence of L-
CC       cysteine; activates transcription from the dlsT(yhaO)-yhaM operon.
CC       {ECO:0000250|UniProtKB:P0ACJ5}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAN79042.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AE014075; AAN79042.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_000884589.1; NC_004431.1.
DR   AlphaFoldDB; P0ACJ6; -.
DR   SMR; P0ACJ6; -.
DR   STRING; 199310.c0564; -.
DR   EnsemblBacteria; AAN79042; AAN79042; c0564.
DR   GeneID; 67416478; -.
DR   KEGG; ecc:c0564; -.
DR   eggNOG; COG1522; Bacteria.
DR   HOGENOM; CLU_091233_0_2_6; -.
DR   OMA; HVSGDYD; -.
DR   Proteomes; UP000001410; Chromosome.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProt.
DR   CDD; cd00090; HTH_ARSR; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR011991; ArsR-like_HTH.
DR   InterPro; IPR000485; AsnC-type_HTH_dom.
DR   InterPro; IPR011008; Dimeric_a/b-barrel.
DR   InterPro; IPR019888; Tscrpt_reg_AsnC-like.
DR   InterPro; IPR019887; Tscrpt_reg_AsnC/Lrp_C.
DR   InterPro; IPR019885; Tscrpt_reg_HTH_AsnC-type_CS.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF01037; AsnC_trans_reg; 1.
DR   PRINTS; PR00033; HTHASNC.
DR   SMART; SM00344; HTH_ASNC; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF54909; SSF54909; 1.
DR   PROSITE; PS00519; HTH_ASNC_1; 1.
DR   PROSITE; PS50956; HTH_ASNC_2; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..152
FT                   /note="DNA-binding transcriptional activator DecR"
FT                   /id="PRO_0000111749"
FT   DOMAIN          2..63
FT                   /note="HTH asnC-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00319"
FT   DNA_BIND        21..40
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00319"
SQ   SEQUENCE   152 AA;  17437 MW;  8409CEDC4CA3D012 CRC64;
     MLDKIDRKLL ALLQQDCTLS LQALAEAVNL TTTPCWKRLK RLEDDGILIG KVALLDPEKI
     GLGLTAFVLI KTQHHSSEWY CRFVTVVTEM PEVLGFWRMA GEYDYLMRVQ VADMKRYDEF
     YKRLVNSVPG LSDVTSSFAM EQIKYTTSLP IE