DEF08_ARATH
ID DEF08_ARATH Reviewed; 80 AA.
AC P82782; Q4VP01;
DT 13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT 29-MAR-2004, sequence version 1.
DT 03-AUG-2022, entry version 91.
DE RecName: Full=Defensin-like protein 8;
DE AltName: Full=Low-molecular-weight cysteine-rich protein 73;
DE Short=Protein LCR73;
DE Flags: Precursor;
GN Name=LCR73; OrderedLocusNames=At2g02147; ORFNames=F5O4;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000305};
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND GENE FAMILY.
RX PubMed=15955924; DOI=10.1104/pp.105.060079;
RA Silverstein K.A.T., Graham M.A., Paape T.D., VandenBosch K.A.;
RT "Genome organization of more than 300 defensin-like genes in Arabidopsis.";
RL Plant Physiol. 138:600-610(2005).
RN [2] {ECO:0000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia {ECO:0000269|PubMed:10617197};
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4] {ECO:0000305}
RP IDENTIFICATION.
RX PubMed=11437247; DOI=10.1023/a:1010664704926;
RA Vanoosthuyse V., Miege C., Dumas C., Cock J.M.;
RT "Two large Arabidopsis thaliana gene families are homologous to the
RT Brassica gene superfamily that encodes pollen coat proteins and the male
RT component of the self-incompatibility response.";
RL Plant Mol. Biol. 46:17-34(2001).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the DEFL family. {ECO:0000305}.
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DR EMBL; AY803261; AAX39302.1; -; mRNA.
DR EMBL; AC005936; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002685; AEC05551.1; -; Genomic_DNA.
DR RefSeq; NP_001030952.1; NM_001035875.2.
DR AlphaFoldDB; P82782; -.
DR SMR; P82782; -.
DR PaxDb; P82782; -.
DR PRIDE; P82782; -.
DR ProteomicsDB; 224612; -.
DR EnsemblPlants; AT2G02147.1; AT2G02147.1; AT2G02147.
DR GeneID; 3768036; -.
DR Gramene; AT2G02147.1; AT2G02147.1; AT2G02147.
DR KEGG; ath:AT2G02147; -.
DR Araport; AT2G02147; -.
DR TAIR; locus:1009023182; AT2G02147.
DR HOGENOM; CLU_161668_0_0_1; -.
DR InParanoid; P82782; -.
DR OMA; NCAIICQ; -.
DR OrthoDB; 1625543at2759; -.
DR PhylomeDB; P82782; -.
DR PRO; PR:P82782; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; P82782; baseline and differential.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
DR Gene3D; 3.30.30.10; -; 1.
DR InterPro; IPR008176; Defensin_plant.
DR InterPro; IPR003614; Scorpion_toxin-like.
DR InterPro; IPR036574; Scorpion_toxin-like_sf.
DR SMART; SM00505; Knot1; 1.
DR SUPFAM; SSF57095; SSF57095; 1.
DR PROSITE; PS00940; GAMMA_THIONIN; 1.
PE 3: Inferred from homology;
KW Antimicrobial; Disulfide bond; Fungicide; Plant defense;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..80
FT /note="Defensin-like protein 8"
FT /id="PRO_0000007027"
FT DISULFID 33..80
FT /evidence="ECO:0000250|UniProtKB:P20158"
FT DISULFID 44..65
FT /evidence="ECO:0000250|UniProtKB:P20158"
FT DISULFID 50..74
FT /evidence="ECO:0000250|UniProtKB:P20158"
FT DISULFID 54..76
FT /evidence="ECO:0000250|UniProtKB:P20158"
SQ SEQUENCE 80 AA; 8986 MW; D7A70745B7E9D059 CRC64;
MKLSLRFLSV LLLIAFMVLA TTAEVSPLDN KICKTRSDRF SGVCISTNNC AIICQQFEHF
DGGHCEFDGA FRRCMCTKQC
