DEF10_ARATH
ID DEF10_ARATH Reviewed; 73 AA.
AC Q9ZUL8; Q0IGN8;
DT 01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 03-AUG-2022, entry version 134.
DE RecName: Full=Defensin-like protein 10;
DE AltName: Full=Low-molecular-weight cysteine-rich protein 72;
DE Short=Protein LCR72;
DE AltName: Full=Plant defensin 2.6;
DE Flags: Precursor;
GN Name=PDF2.6; Synonyms=LCR72; OrderedLocusNames=At2g02140; ORFNames=F5O4.9;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Bautista V.R., Kim C.J., Chen H., Quinitio C., Ecker J.R.;
RT "Arabidopsis ORF Clones.";
RL Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP IDENTIFICATION.
RX PubMed=11437247; DOI=10.1023/a:1010664704926;
RA Vanoosthuyse V., Miege C., Dumas C., Cock J.M.;
RT "Two large Arabidopsis thaliana gene families are homologous to the
RT Brassica gene superfamily that encodes pollen coat proteins and the male
RT component of the self-incompatibility response.";
RL Plant Mol. Biol. 46:17-34(2001).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12447532; DOI=10.1007/s00425-002-0902-6;
RA Thomma B.P.H.J., Cammue B.P., Thevissen K.;
RT "Plant defensins.";
RL Planta 216:193-202(2002).
RN [7]
RP GENE FAMILY.
RX PubMed=15955924; DOI=10.1104/pp.105.060079;
RA Silverstein K.A.T., Graham M.A., Paape T.D., VandenBosch K.A.;
RT "Genome organization of more than 300 defensin-like genes in Arabidopsis.";
RL Plant Physiol. 138:600-610(2005).
CC -!- FUNCTION: Confers broad-spectrum resistance to pathogens.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the DEFL family. {ECO:0000305}.
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DR EMBL; AC005936; AAC97220.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC05550.1; -; Genomic_DNA.
DR EMBL; BT028882; ABI49429.1; -; mRNA.
DR EMBL; AY087062; AAM64623.1; -; mRNA.
DR PIR; D84433; D84433.
DR RefSeq; NP_178322.1; NM_126274.3.
DR AlphaFoldDB; Q9ZUL8; -.
DR SMR; Q9ZUL8; -.
DR BioGRID; 148; 1.
DR STRING; 3702.AT2G02140.1; -.
DR PaxDb; Q9ZUL8; -.
DR PRIDE; Q9ZUL8; -.
DR ProteomicsDB; 224173; -.
DR EnsemblPlants; AT2G02140.1; AT2G02140.1; AT2G02140.
DR GeneID; 814745; -.
DR Gramene; AT2G02140.1; AT2G02140.1; AT2G02140.
DR KEGG; ath:AT2G02140; -.
DR Araport; AT2G02140; -.
DR TAIR; locus:2051703; AT2G02140.
DR HOGENOM; CLU_161668_1_2_1; -.
DR InParanoid; Q9ZUL8; -.
DR OMA; SLRCYCS; -.
DR OrthoDB; 1625543at2759; -.
DR PhylomeDB; Q9ZUL8; -.
DR PRO; PR:Q9ZUL8; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9ZUL8; baseline and differential.
DR Genevisible; Q9ZUL8; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0006952; P:defense response; ISS:TAIR.
DR GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
DR CDD; cd00107; Knot1; 1.
DR Gene3D; 3.30.30.10; -; 1.
DR InterPro; IPR008176; Defensin_plant.
DR InterPro; IPR003614; Scorpion_toxin-like.
DR InterPro; IPR036574; Scorpion_toxin-like_sf.
DR PRINTS; PR00288; PUROTHIONIN.
DR SMART; SM00505; Knot1; 1.
DR SUPFAM; SSF57095; SSF57095; 1.
DR PROSITE; PS00940; GAMMA_THIONIN; 1.
PE 3: Inferred from homology;
KW Antimicrobial; Disulfide bond; Fungicide; Plant defense;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..28
FT /evidence="ECO:0000255"
FT CHAIN 29..73
FT /note="Defensin-like protein 10"
FT /id="PRO_0000007026"
FT DISULFID 31..73
FT /evidence="ECO:0000250"
FT DISULFID 42..62
FT /evidence="ECO:0000250"
FT DISULFID 48..67
FT /evidence="ECO:0000250"
FT DISULFID 52..69
FT /evidence="ECO:0000250"
SQ SEQUENCE 73 AA; 7718 MW; DA27D295AC3739DA CRC64;
MKLSLRLISA LLMSVMLLFA TGMGPVEART CESPSNKFQG VCLNSQSCAK ACPSEGFSGG
RCSSLRCYCS KAC
