DEF12_ARATH
ID DEF12_ARATH Reviewed; 74 AA.
AC Q2V477;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 10-JAN-2006, sequence version 1.
DT 03-AUG-2022, entry version 64.
DE RecName: Full=Putative defensin-like protein 12;
DE Flags: Precursor;
GN OrderedLocusNames=At2g19893; ORFNames=F6F22;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY.
RX PubMed=15955924; DOI=10.1104/pp.105.060079;
RA Silverstein K.A.T., Graham M.A., Paape T.D., VandenBosch K.A.;
RT "Genome organization of more than 300 defensin-like genes in Arabidopsis.";
RL Plant Physiol. 138:600-610(2005).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the DEFL family. {ECO:0000305}.
CC -!- CAUTION: Lacks 1 of the 4 disulfide bonds, which are conserved features
CC of the family. {ECO:0000305}.
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DR EMBL; AC005169; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002685; AEC06940.1; -; Genomic_DNA.
DR RefSeq; NP_001031376.1; NM_001036299.1.
DR AlphaFoldDB; Q2V477; -.
DR SMR; Q2V477; -.
DR STRING; 3702.AT2G19893.1; -.
DR PaxDb; Q2V477; -.
DR PRIDE; Q2V477; -.
DR EnsemblPlants; AT2G19893.1; AT2G19893.1; AT2G19893.
DR GeneID; 3768542; -.
DR Gramene; AT2G19893.1; AT2G19893.1; AT2G19893.
DR KEGG; ath:AT2G19893; -.
DR Araport; AT2G19893; -.
DR TAIR; locus:1009023170; AT2G19893.
DR HOGENOM; CLU_2691146_0_0_1; -.
DR OMA; MAKPCAA; -.
DR OrthoDB; 1626735at2759; -.
DR PRO; PR:Q2V477; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q2V477; baseline and differential.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
PE 3: Inferred from homology;
KW Antimicrobial; Disulfide bond; Fungicide; Plant defense;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..26
FT /evidence="ECO:0000255"
FT CHAIN 27..74
FT /note="Putative defensin-like protein 12"
FT /id="PRO_0000379599"
FT DISULFID 26..50
FT /evidence="ECO:0000250"
FT DISULFID 33..59
FT /evidence="ECO:0000250"
FT DISULFID 39..61
FT /evidence="ECO:0000250"
SQ SEQUENCE 74 AA; 8245 MW; E6D8253BC46611C3 CRC64;
MAKPCAAFLV FLCLSMLILS IPDISCQMND CDCDHDHRCG EWEDESHGNC KQHHLRVVCT
CTLDCLDISS TSNA
