DEF15_ARATH
ID DEF15_ARATH Reviewed; 80 AA.
AC O80994;
DT 01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 25-MAY-2022, entry version 123.
DE RecName: Full=Putative defensin-like protein 15;
DE AltName: Full=Putative cysteine-rich antifungal protein At2g26020;
DE AltName: Full=Putative plant defensin 1.2b;
DE Flags: Precursor;
GN Name=PDF1.2B; OrderedLocusNames=At2g26020; ORFNames=T19L18.17;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12447532; DOI=10.1007/s00425-002-0902-6;
RA Thomma B.P.H.J., Cammue B.P., Thevissen K.;
RT "Plant defensins.";
RL Planta 216:193-202(2002).
RN [4]
RP GENE FAMILY.
RX PubMed=15955924; DOI=10.1104/pp.105.060079;
RA Silverstein K.A.T., Graham M.A., Paape T.D., VandenBosch K.A.;
RT "Genome organization of more than 300 defensin-like genes in Arabidopsis.";
RL Plant Physiol. 138:600-610(2005).
CC -!- FUNCTION: Confers broad-spectrum resistance to pathogens.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the DEFL family. {ECO:0000305}.
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DR EMBL; AC004747; AAC31244.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC07784.1; -; Genomic_DNA.
DR PIR; T02621; T02621.
DR RefSeq; NP_180172.1; NM_128161.2.
DR AlphaFoldDB; O80994; -.
DR SMR; O80994; -.
DR STRING; 3702.AT2G26020.1; -.
DR PaxDb; O80994; -.
DR ProteomicsDB; 224069; -.
DR EnsemblPlants; AT2G26020.1; AT2G26020.1; AT2G26020.
DR GeneID; 817143; -.
DR Gramene; AT2G26020.1; AT2G26020.1; AT2G26020.
DR KEGG; ath:AT2G26020; -.
DR Araport; AT2G26020; -.
DR TAIR; locus:2057437; AT2G26020.
DR eggNOG; ENOG502SQS4; Eukaryota.
DR HOGENOM; CLU_161668_3_0_1; -.
DR InParanoid; O80994; -.
DR OrthoDB; 1565340at2759; -.
DR PhylomeDB; O80994; -.
DR PRO; PR:O80994; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O80994; baseline and differential.
DR Genevisible; O80994; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0006952; P:defense response; ISS:TAIR.
DR GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
DR CDD; cd00107; Knot1; 1.
DR Gene3D; 3.30.30.10; -; 1.
DR InterPro; IPR008176; Defensin_plant.
DR InterPro; IPR003614; Scorpion_toxin-like.
DR InterPro; IPR036574; Scorpion_toxin-like_sf.
DR SMART; SM00505; Knot1; 1.
DR SUPFAM; SSF57095; SSF57095; 1.
DR PROSITE; PS00940; GAMMA_THIONIN; 1.
PE 3: Inferred from homology;
KW Antimicrobial; Disulfide bond; Fungicide; Plant defense;
KW Pyrrolidone carboxylic acid; Reference proteome; Secreted; Signal.
FT SIGNAL 1..29
FT /evidence="ECO:0000250"
FT CHAIN 30..80
FT /note="Putative defensin-like protein 15"
FT /id="PRO_0000007021"
FT MOD_RES 30
FT /note="Pyrrolidone carboxylic acid"
FT /evidence="ECO:0000250|UniProtKB:P30224"
FT DISULFID 33..80
FT /evidence="ECO:0000250"
FT DISULFID 44..65
FT /evidence="ECO:0000250"
FT DISULFID 50..74
FT /evidence="ECO:0000250"
FT DISULFID 54..76
FT /evidence="ECO:0000250"
SQ SEQUENCE 80 AA; 8640 MW; 81B106058BAFFCC7 CRC64;
MAKFASIITF IYAALVLFAA FEVPTMVEAQ KLCEKPSGTW SGVCGNSNAC KNQCINLEGA
KHGSCNYVFP AHKCICYVPC
