DEF17_ARATH
ID DEF17_ARATH Reviewed; 80 AA.
AC Q9FI22;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 93.
DE RecName: Full=Defensin-like protein 17;
DE AltName: Full=Plant defensin 1.2c;
DE Flags: Precursor;
GN Name=PDF1.2C; OrderedLocusNames=At5g44430; ORFNames=MFC16.9;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10470850; DOI=10.1093/dnares/6.3.183;
RA Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Kotani H.,
RA Miyajima N., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. IX. Sequence
RT features of the regions of 1,011,550 bp covered by seventeen P1 and TAC
RT clones.";
RL DNA Res. 6:183-195(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12447532; DOI=10.1007/s00425-002-0902-6;
RA Thomma B.P.H.J., Cammue B.P., Thevissen K.;
RT "Plant defensins.";
RL Planta 216:193-202(2002).
RN [4]
RP GENE FAMILY.
RX PubMed=15955924; DOI=10.1104/pp.105.060079;
RA Silverstein K.A.T., Graham M.A., Paape T.D., VandenBosch K.A.;
RT "Genome organization of more than 300 defensin-like genes in Arabidopsis.";
RL Plant Physiol. 138:600-610(2005).
CC -!- FUNCTION: Confers broad-spectrum resistance to pathogens.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the DEFL family. {ECO:0000305}.
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DR EMBL; AB017065; BAB09150.1; -; Genomic_DNA.
DR EMBL; CP002688; AED95108.1; -; Genomic_DNA.
DR RefSeq; NP_199256.1; NM_123810.3.
DR AlphaFoldDB; Q9FI22; -.
DR SMR; Q9FI22; -.
DR STRING; 3702.AT5G44430.1; -.
DR PaxDb; Q9FI22; -.
DR PRIDE; Q9FI22; -.
DR EnsemblPlants; AT5G44430.1; AT5G44430.1; AT5G44430.
DR GeneID; 834470; -.
DR Gramene; AT5G44430.1; AT5G44430.1; AT5G44430.
DR KEGG; ath:AT5G44430; -.
DR Araport; AT5G44430; -.
DR TAIR; locus:2163431; AT5G44430.
DR eggNOG; ENOG502SQS4; Eukaryota.
DR HOGENOM; CLU_161668_3_0_1; -.
DR InParanoid; Q9FI22; -.
DR OMA; PARKCIC; -.
DR OrthoDB; 1565340at2759; -.
DR PhylomeDB; Q9FI22; -.
DR PRO; PR:Q9FI22; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FI22; baseline and differential.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0006952; P:defense response; ISS:TAIR.
DR GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
DR CDD; cd00107; Knot1; 1.
DR Gene3D; 3.30.30.10; -; 1.
DR InterPro; IPR008176; Defensin_plant.
DR InterPro; IPR003614; Scorpion_toxin-like.
DR InterPro; IPR036574; Scorpion_toxin-like_sf.
DR SMART; SM00505; Knot1; 1.
DR SUPFAM; SSF57095; SSF57095; 1.
DR PROSITE; PS00940; GAMMA_THIONIN; 1.
PE 2: Evidence at transcript level;
KW Antimicrobial; Disulfide bond; Fungicide; Plant defense;
KW Pyrrolidone carboxylic acid; Reference proteome; Secreted; Signal.
FT SIGNAL 1..29
FT /evidence="ECO:0000250"
FT CHAIN 30..80
FT /note="Defensin-like protein 17"
FT /id="PRO_0000379600"
FT MOD_RES 30
FT /note="Pyrrolidone carboxylic acid"
FT /evidence="ECO:0000250|UniProtKB:P30224"
FT DISULFID 33..80
FT /evidence="ECO:0000250"
FT DISULFID 44..65
FT /evidence="ECO:0000250"
FT DISULFID 50..74
FT /evidence="ECO:0000250"
FT DISULFID 54..76
FT /evidence="ECO:0000250"
SQ SEQUENCE 80 AA; 8550 MW; 44E1F6D8452AC76E CRC64;
MAKSATIITF LFAALVLFAA FEAPTMVEAQ KLCEKPSGTW SGVCGNSNAC KNQCINLEGA
KHGSCNYVFP AHKCICYVPC
