ID   DEF21_SORBI             Reviewed;          47 AA.
AC   Q09198;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   25-MAY-2022, entry version 66.
DE   RecName: Full=Defensin-like protein 21;
DE   AltName: Full=Small protein inhibitor of insect alpha-amylases 2.1;
DE            Short=SI alpha-2.1;
OS   Sorghum bicolor (Sorghum) (Sorghum vulgare).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Sorghinae; Sorghum.
OX   NCBI_TaxID=4558;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Seed;
RX   PubMed=7705336; DOI=10.1111/j.1432-1033.1995.tb20257.x;
RA   Nitti G., Orru S., Bloch C. Jr., Morhy L., Marino G., Pucci P.;
RT   "Amino acid sequence and disulphide-bridge pattern of three gamma-thionins
RT   from Sorghum bicolor.";
RL   Eur. J. Biochem. 228:250-256(1995).
CC   -!- SIMILARITY: Belongs to the DEFL family. Protease inhibitor I18
CC       (RTI/MTI-2) subfamily. {ECO:0000305}.
CC   -!- CAUTION: Was initially thought to be a protease inhibitor.
CC       {ECO:0000305|PubMed:7705336}.
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DR   PIR; S69144; S69144.
DR   AlphaFoldDB; Q09198; -.
DR   SMR; Q09198; -.
DR   EnsemblPlants; OQU80072; OQU80072; SORBI_3007G075301.
DR   Gramene; OQU80072; OQU80072; SORBI_3007G075301.
DR   ExpressionAtlas; Q09198; baseline.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
DR   CDD; cd00107; Knot1; 1.
DR   Gene3D; 3.30.30.10; -; 1.
DR   InterPro; IPR008176; Defensin_plant.
DR   InterPro; IPR003614; Scorpion_toxin-like.
DR   InterPro; IPR036574; Scorpion_toxin-like_sf.
DR   PRINTS; PR00288; PUROTHIONIN.
DR   SMART; SM00505; Knot1; 1.
DR   SUPFAM; SSF57095; SSF57095; 1.
DR   PROSITE; PS00940; GAMMA_THIONIN; 1.
PE   1: Evidence at protein level;
KW   Antimicrobial; Direct protein sequencing; Disulfide bond; Fungicide;
KW   Plant defense.
FT   CHAIN           1..47
FT                   /note="Defensin-like protein 21"
FT                   /id="PRO_0000074247"
FT   DISULFID        3..47
FT                   /evidence="ECO:0000269|PubMed:7705336"
FT   DISULFID        14..34
FT                   /evidence="ECO:0000269|PubMed:7705336"
FT   DISULFID        20..41
FT                   /evidence="ECO:0000269|PubMed:7705336"
FT   DISULFID        24..43
FT                   /evidence="ECO:0000269|PubMed:7705336"
SQ   SEQUENCE   47 AA;  5222 MW;  0F3A72B967DBBDFE CRC64;
     RVCRRRSAGF KGLCMSDHNC AQVCLQEGWG GGNCDGVMRQ CKCIRQC