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DEF22_ARATH
ID   DEF22_ARATH             Reviewed;          82 AA.
AC   Q2V391;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-JAN-2006, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Defensin-like protein 22;
DE   Flags: Precursor;
GN   OrderedLocusNames=At5g08315; ORFNames=F8L15;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130714; DOI=10.1038/35048507;
RA   Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA   Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA   Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA   Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA   Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA   O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA   Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA   Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA   Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA   Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA   Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA   Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA   Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA   Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA   Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA   Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA   McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA   Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA   Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA   Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA   Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA   Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA   Bevan M., Fransz P.F.;
RT   "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL   Nature 408:823-826(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENE FAMILY.
RX   PubMed=15955924; DOI=10.1104/pp.105.060079;
RA   Silverstein K.A.T., Graham M.A., Paape T.D., VandenBosch K.A.;
RT   "Genome organization of more than 300 defensin-like genes in Arabidopsis.";
RL   Plant Physiol. 138:600-610(2005).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the DEFL family. {ECO:0000305}.
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DR   EMBL; AL392174; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CP002688; AED91282.1; -; Genomic_DNA.
DR   RefSeq; NP_001031854.1; NM_001036777.2.
DR   AlphaFoldDB; Q2V391; -.
DR   PaxDb; Q2V391; -.
DR   PRIDE; Q2V391; -.
DR   ProteomicsDB; 224112; -.
DR   EnsemblPlants; AT5G08315.1; AT5G08315.1; AT5G08315.
DR   GeneID; 3770708; -.
DR   Gramene; AT5G08315.1; AT5G08315.1; AT5G08315.
DR   KEGG; ath:AT5G08315; -.
DR   Araport; AT5G08315; -.
DR   TAIR; locus:1009023410; AT5G08315.
DR   HOGENOM; CLU_185732_0_0_1; -.
DR   InParanoid; Q2V391; -.
DR   OMA; NTKNDDQ; -.
DR   OrthoDB; 1610709at2759; -.
DR   PhylomeDB; Q2V391; -.
DR   PRO; PR:Q2V391; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q2V391; baseline.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
DR   InterPro; IPR022618; Defensin-like_20-27.
DR   PANTHER; PTHR34453; PTHR34453; 1.
DR   Pfam; PF10868; Defensin_like; 1.
PE   2: Evidence at transcript level;
KW   Antimicrobial; Disulfide bond; Fungicide; Plant defense;
KW   Reference proteome; Secreted; Signal.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..82
FT                   /note="Defensin-like protein 22"
FT                   /id="PRO_0000379604"
FT   DISULFID        34..82
FT                   /evidence="ECO:0000250"
FT   DISULFID        44..69
FT                   /evidence="ECO:0000250"
FT   DISULFID        53..78
FT                   /evidence="ECO:0000250"
FT   DISULFID        57..80
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   82 AA;  8935 MW;  AD006603E36B0A5E CRC64;
     MAGLKVFSFA LLLILTFSLI DVEGYNVENG GSLCCNNHPK FGKCNTKNDD QRCNSWCLNG
     CDNGKGGYCK SMSHGGQCHC YC
 
 
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