ID   DEF2_CAPAN              Reviewed;          74 AA.
AC   O65740;
DT   26-SEP-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Defensin J1-2;
DE   Flags: Precursor;
OS   Capsicum annuum (Capsicum pepper).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Solanoideae; Capsiceae; Capsicum.
OX   NCBI_TaxID=4072;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND CHARACTERIZATION.
RC   STRAIN=cv. Yolo Wonder; TISSUE=Fruit;
RX   PubMed=8883377; DOI=10.1104/pp.112.2.615;
RA   Meyer B., Houlne G., Pozueta-Romero J., Schantz M.L., Schantz R.;
RT   "Fruit-specific expression of a defensin-type gene family in bell pepper.
RT   Upregulation during ripening and upon wounding.";
RL   Plant Physiol. 112:615-622(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND CHARACTERIZATION.
RC   STRAIN=cv. Yolo Wonder; TISSUE=Fruit;
RX   PubMed=9790581; DOI=10.1007/s004380050841;
RA   Houlne G., Meyer B., Schantz R.;
RT   "Alteration of the expression of a plant defensin gene by exon shuffling in
RT   bell pepper (Capsicum annuum L.).";
RL   Mol. Gen. Genet. 259:504-510(1998).
CC   -!- FUNCTION: Plant defense peptide with antifungal activity against
CC       F.oxysporum and B.cinerea.
CC   -!- SUBUNIT: Monomer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Expressed in flowers and in young fruits.
CC   -!- DEVELOPMENTAL STAGE: Accumulates during ripening.
CC   -!- SIMILARITY: Belongs to the DEFL family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X95730; CAA65046.1; -; Genomic_DNA.
DR   RefSeq; XP_016537481.1; XM_016681995.1.
DR   AlphaFoldDB; O65740; -.
DR   SMR; O65740; -.
DR   TCDB; 1.C.45.1.5; the plant defensin (plant defensin) family.
DR   GeneID; 107838795; -.
DR   KEGG; cann:107838795; -.
DR   OrthoDB; 1625543at2759; -.
DR   Proteomes; UP000189700; Chromosome 8.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
DR   CDD; cd00107; Knot1; 1.
DR   Gene3D; 3.30.30.10; -; 1.
DR   InterPro; IPR008176; Defensin_plant.
DR   InterPro; IPR003614; Scorpion_toxin-like.
DR   InterPro; IPR036574; Scorpion_toxin-like_sf.
DR   PRINTS; PR00288; PUROTHIONIN.
DR   SMART; SM00505; Knot1; 1.
DR   SUPFAM; SSF57095; SSF57095; 1.
DR   PROSITE; PS00940; GAMMA_THIONIN; 1.
PE   1: Evidence at protein level;
KW   Antimicrobial; Disulfide bond; Fungicide; Plant defense; Secreted; Signal.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000250"
FT   CHAIN           28..74
FT                   /note="Defensin J1-2"
FT                   /id="PRO_0000007037"
FT   DISULFID        30..74
FT                   /evidence="ECO:0000250"
FT   DISULFID        41..61
FT                   /evidence="ECO:0000250"
FT   DISULFID        47..68
FT                   /evidence="ECO:0000250"
FT   DISULFID        51..70
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   74 AA;  8249 MW;  D92D8F06F39E1552 CRC64;
     MAGFSKVIAT IFLMMMLVFA TGMVAEARTC ESQSHRFKGL CFSKSNCGSV CHTEGFNGGH
     CRGFRRRCFC TRHC