ID   DEF2_VICFA              Reviewed;          47 AA.
AC   P81457;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-1998, sequence version 1.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Defensin-like protein 2;
DE   AltName: Full=Fabatin-2;
OS   Vicia faba (Broad bean) (Faba vulgaris).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC   NPAAA clade; Hologalegina; IRL clade; Fabeae; Vicia.
OX   NCBI_TaxID=3906;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Seed;
RX   PubMed=9103978; DOI=10.1111/j.1574-6968.1997.tb10308.x;
RA   Zhang Y., Lewis K.;
RT   "Fabatins: new antimicrobial plant peptides.";
RL   FEMS Microbiol. Lett. 149:59-64(1997).
CC   -!- FUNCTION: Fabatins have antibacterial activity against Gram-positive
CC       and Gram-negative bacteria. High activity against P.aeruginosa. No
CC       activity against S.cerevisiae and C.albicans.
CC   -!- SIMILARITY: Belongs to the DEFL family. {ECO:0000305}.
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DR   PIR; B58445; B58445.
DR   AlphaFoldDB; P81457; -.
DR   SMR; P81457; -.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
DR   CDD; cd00107; Knot1; 1.
DR   Gene3D; 3.30.30.10; -; 1.
DR   InterPro; IPR008176; Defensin_plant.
DR   InterPro; IPR003614; Scorpion_toxin-like.
DR   InterPro; IPR036574; Scorpion_toxin-like_sf.
DR   PRINTS; PR00288; PUROTHIONIN.
DR   SMART; SM00505; Knot1; 1.
DR   SUPFAM; SSF57095; SSF57095; 1.
DR   PROSITE; PS00940; GAMMA_THIONIN; 1.
PE   1: Evidence at protein level;
KW   Antibiotic; Antimicrobial; Direct protein sequencing; Disulfide bond;
KW   Fungicide; Plant defense.
FT   CHAIN           1..47
FT                   /note="Defensin-like protein 2"
FT                   /id="PRO_0000074259"
FT   DISULFID        5..47
FT                   /evidence="ECO:0000250"
FT   DISULFID        16..36
FT                   /evidence="ECO:0000250"
FT   DISULFID        22..43
FT                   /evidence="ECO:0000250"
FT   DISULFID        26..45
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   47 AA;  5206 MW;  A9D4E9AC1D920A69 CRC64;
     LLGRCKVKSN RFNGPCLTDT HCSTVCRGEG YKGGDCHGLR RRCMCLC