ID   DEF35_ARATH             Reviewed;          72 AA.
AC   Q2V4F3; Q9SH70;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 2.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Defensin-like protein 35;
DE   Flags: Precursor;
GN   OrderedLocusNames=At1g64195; ORFNames=F22C12.4;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENE FAMILY.
RX   PubMed=15955924; DOI=10.1104/pp.105.060079;
RA   Silverstein K.A.T., Graham M.A., Paape T.D., VandenBosch K.A.;
RT   "Genome organization of more than 300 defensin-like genes in Arabidopsis.";
RL   Plant Physiol. 138:600-610(2005).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the DEFL family. {ECO:0000305}.
CC   -!- CAUTION: Lacks 1 of the 4 disulfide bonds, which are conserved features
CC       of the family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAF24559.1; Type=Erroneous gene model prediction; Note=The predicted gene has been split into 2 genes: At1g64195 and At1g64200.; Evidence={ECO:0000305};
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DR   EMBL; AC007764; AAF24559.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002684; AEE34208.1; -; Genomic_DNA.
DR   PIR; C96666; C96666.
DR   RefSeq; NP_001031227.2; NM_001036150.3.
DR   AlphaFoldDB; Q2V4F3; -.
DR   SMR; Q2V4F3; -.
DR   STRING; 3702.AT1G64195.1; -.
DR   PaxDb; Q2V4F3; -.
DR   PRIDE; Q2V4F3; -.
DR   EnsemblPlants; AT1G64195.1; AT1G64195.1; AT1G64195.
DR   GeneID; 3767629; -.
DR   Gramene; AT1G64195.1; AT1G64195.1; AT1G64195.
DR   KEGG; ath:AT1G64195; -.
DR   Araport; AT1G64195; -.
DR   TAIR; locus:1009023089; AT1G64195.
DR   HOGENOM; CLU_2725643_0_0_1; -.
DR   OMA; MCECYEG; -.
DR   OrthoDB; 1554653at2759; -.
DR   PhylomeDB; Q2V4F3; -.
DR   PRO; PR:Q2V4F3; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; Q2V4F3; baseline and differential.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
PE   2: Evidence at transcript level;
KW   Antimicrobial; Disulfide bond; Fungicide; Plant defense;
KW   Reference proteome; Secreted; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..72
FT                   /note="Defensin-like protein 35"
FT                   /id="PRO_0000379617"
FT   DISULFID        32..58
FT                   /evidence="ECO:0000250"
FT   DISULFID        44..67
FT                   /evidence="ECO:0000250"
FT   DISULFID        48..69
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   72 AA;  7913 MW;  3BC2B6D90C658634 CRC64;
     MASNKISFSF VLCLYMCSLL DAKSMNPTGR RCPDPNGVEK KSMCYSSCKT QGFMGGSCQG
     HKGNYMCECY EG