DEF50_ARATH
ID DEF50_ARATH Reviewed; 80 AA.
AC P82764;
DT 13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 1.
DT 03-AUG-2022, entry version 79.
DE RecName: Full=Defensin-like protein 50;
DE AltName: Full=Low-molecular-weight cysteine-rich protein 49;
DE Short=Protein LCR49;
DE Flags: Precursor;
GN Name=LCR49; OrderedLocusNames=At2g33233; ORFNames=F25I18;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000305};
RN [1] {ECO:0000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=17229318; DOI=10.1186/1471-2164-8-18;
RA Moskal W.A. Jr., Wu H.C., Underwood B.A., Wang W., Town C.D., Xiao Y.-L.;
RT "Experimental validation of novel genes predicted in the un-annotated
RT regions of the Arabidopsis genome.";
RL BMC Genomics 8:18-18(2007).
RN [4] {ECO:0000305}
RP IDENTIFICATION.
RX PubMed=11437247; DOI=10.1023/a:1010664704926;
RA Vanoosthuyse V., Miege C., Dumas C., Cock J.M.;
RT "Two large Arabidopsis thaliana gene families are homologous to the
RT Brassica gene superfamily that encodes pollen coat proteins and the male
RT component of the self-incompatibility response.";
RL Plant Mol. Biol. 46:17-34(2001).
RN [5]
RP GENE FAMILY.
RX PubMed=15955924; DOI=10.1104/pp.105.060079;
RA Silverstein K.A.T., Graham M.A., Paape T.D., VandenBosch K.A.;
RT "Genome organization of more than 300 defensin-like genes in Arabidopsis.";
RL Plant Physiol. 138:600-610(2005).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the DEFL family. {ECO:0000305}.
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DR EMBL; AC002334; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002685; AEC08803.1; -; Genomic_DNA.
DR EMBL; EF182866; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; NP_001031470.1; NM_001036393.2.
DR AlphaFoldDB; P82764; -.
DR SMR; P82764; -.
DR STRING; 3702.AT2G33233.1; -.
DR PaxDb; P82764; -.
DR PRIDE; P82764; -.
DR EnsemblPlants; AT2G33233.1; AT2G33233.1; AT2G33233.
DR GeneID; 3768712; -.
DR Gramene; AT2G33233.1; AT2G33233.1; AT2G33233.
DR KEGG; ath:AT2G33233; -.
DR Araport; AT2G33233; -.
DR TAIR; locus:1009023227; AT2G33233.
DR HOGENOM; CLU_165205_1_0_1; -.
DR OMA; LEITCTM; -.
DR OrthoDB; 1614859at2759; -.
DR PhylomeDB; P82764; -.
DR PRO; PR:P82764; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; P82764; baseline.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
PE 3: Inferred from homology;
KW Antimicrobial; Disulfide bond; Fungicide; Plant defense;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..27
FT /evidence="ECO:0000255"
FT CHAIN 28..80
FT /note="Defensin-like protein 50"
FT /id="PRO_0000017288"
FT DISULFID 39..79
FT /evidence="ECO:0000250"
FT DISULFID 43..66
FT /evidence="ECO:0000250"
FT DISULFID 52..77
FT /evidence="ECO:0000250"
FT DISULFID 56..78
FT /evidence="ECO:0000250"
SQ SEQUENCE 80 AA; 8738 MW; 26FEB242E2CC2FA8 CRC64;
MGFTKIVVTF FLVVMLAVSS SSQNAMASEI KAKINGLECF NTCTPYYDDY KCNVDCLSSG
YPAGDCHIVS PSQPKKCCCY
