DEF58_ARATH
ID DEF58_ARATH Reviewed; 75 AA.
AC Q4VNZ9; F4IU82; F4IU83;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 28-JUL-2009, sequence version 2.
DT 03-AUG-2022, entry version 62.
DE RecName: Full=Defensin-like protein 58;
DE Flags: Precursor;
GN OrderedLocusNames=At2g03937; ORFNames=F3C11;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 17-74, AND GENE FAMILY.
RX PubMed=15955924; DOI=10.1104/pp.105.060079;
RA Silverstein K.A.T., Graham M.A., Paape T.D., VandenBosch K.A.;
RT "Genome organization of more than 300 defensin-like genes in Arabidopsis.";
RL Plant Physiol. 138:600-610(2005).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q4VNZ9-1; Sequence=Displayed;
CC -!- SIMILARITY: Belongs to the DEFL family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AC007167; Type=Frameshift; Evidence={ECO:0000305};
CC Sequence=AEC05772.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=AEC05772.1; Type=Frameshift; Evidence={ECO:0000305};
CC Sequence=AEC05773.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=AEC05773.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; AC007167; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002685; AEC05772.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002685; AEC05773.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AY803263; AAX39304.1; -; mRNA.
DR RefSeq; NP_001031312.1; NM_001036235.1.
DR RefSeq; NP_001031313.1; NM_001036236.2.
DR AlphaFoldDB; Q4VNZ9; -.
DR SMR; Q4VNZ9; -.
DR STRING; 3702.AT2G03937.2; -.
DR PaxDb; Q4VNZ9; -.
DR PRIDE; Q4VNZ9; -.
DR GeneID; 3768675; -.
DR KEGG; ath:AT2G03937; -.
DR Araport; AT2G03937; -.
DR TAIR; locus:1009023158; AT2G03937.
DR OrthoDB; 240367at33090; -.
DR PhylomeDB; Q4VNZ9; -.
DR PRO; PR:Q4VNZ9; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q4VNZ9; baseline and differential.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
PE 3: Inferred from homology;
KW Alternative splicing; Antimicrobial; Disulfide bond; Fungicide;
KW Plant defense; Reference proteome; Secreted; Signal.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..75
FT /note="Defensin-like protein 58"
FT /id="PRO_0000379638"
FT DISULFID 39..73
FT /evidence="ECO:0000250"
FT DISULFID 43..66
FT /evidence="ECO:0000250"
FT DISULFID 52..71
FT /evidence="ECO:0000250"
FT DISULFID 56..72
FT /evidence="ECO:0000250"
SQ SEQUENCE 75 AA; 8519 MW; 6E0CCBE74A76BCA7 CRC64;
MNITKRYVVI FFLVMLTKSL SNSDVLVSSV IETSKNDVCF IPCTRRYGDW ECYDDCLGKN
FNDGGCVDGR CCCKK