ID   DEF68_ARATH             Reviewed;          98 AA.
AC   Q2V4L5; A0MJT8; Q9LR89;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-JAN-2006, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Defensin-like protein 68;
DE   Flags: Precursor;
GN   OrderedLocusNames=At1g24062; ORFNames=T23E23.21;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA   Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT   "Simultaneous high-throughput recombinational cloning of open reading
RT   frames in closed and open configurations.";
RL   Plant Biotechnol. J. 4:317-324(2006).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=17229318; DOI=10.1186/1471-2164-8-18;
RA   Moskal W.A. Jr., Wu H.C., Underwood B.A., Wang W., Town C.D., Xiao Y.-L.;
RT   "Experimental validation of novel genes predicted in the un-annotated
RT   regions of the Arabidopsis genome.";
RL   BMC Genomics 8:18-18(2007).
RN   [5]
RP   GENE FAMILY.
RX   PubMed=15955924; DOI=10.1104/pp.105.060079;
RA   Silverstein K.A.T., Graham M.A., Paape T.D., VandenBosch K.A.;
RT   "Genome organization of more than 300 defensin-like genes in Arabidopsis.";
RL   Plant Physiol. 138:600-610(2005).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the DEFL family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAF87150.1; Type=Erroneous gene model prediction; Note=The predicted gene has been split into 2 genes: At1g24060 and At1g24062.; Evidence={ECO:0000305};
CC       Sequence=ABK27947.1; Type=Erroneous termination; Note=Extended C-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AC002423; AAF87150.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002684; AEE30474.1; -; Genomic_DNA.
DR   EMBL; DQ912185; ABI34007.1; -; mRNA.
DR   EMBL; DQ912237; ABK27947.1; ALT_SEQ; mRNA.
DR   EMBL; EF182856; -; NOT_ANNOTATED_CDS; mRNA.
DR   RefSeq; NP_001031087.1; NM_001036010.2.
DR   AlphaFoldDB; Q2V4L5; -.
DR   STRING; 3702.AT1G24062.1; -.
DR   PaxDb; Q2V4L5; -.
DR   EnsemblPlants; AT1G24062.1; AT1G24062.1; AT1G24062.
DR   GeneID; 3766789; -.
DR   Gramene; AT1G24062.1; AT1G24062.1; AT1G24062.
DR   KEGG; ath:AT1G24062; -.
DR   Araport; AT1G24062; -.
DR   TAIR; locus:1009023138; AT1G24062.
DR   HOGENOM; CLU_175051_0_0_1; -.
DR   OrthoDB; 1533053at2759; -.
DR   PhylomeDB; Q2V4L5; -.
DR   PRO; PR:Q2V4L5; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; Q2V4L5; baseline and differential.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Antimicrobial; Disulfide bond; Fungicide; Plant defense;
KW   Reference proteome; Secreted; Signal.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   CHAIN           20..98
FT                   /note="Defensin-like protein 68"
FT                   /id="PRO_0000379646"
FT   DISULFID        38..88
FT                   /evidence="ECO:0000250"
FT   DISULFID        42..65
FT                   /evidence="ECO:0000250"
FT   DISULFID        51..86
FT                   /evidence="ECO:0000250"
FT   DISULFID        55..87
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   98 AA;  10687 MW;  FC694E4E861C6AC2 CRC64;
     MGSSKLLVAL TLVVMITISY DLFSEIGISA ATLVIPTCFE NCNATFQDPE CNKWCALLAY
     KDGSCLYPPS EVDDLPPIKR PYIPRCCCNP ITLSPPSP